Cell Structure Flashcards

1
Q

M phase

A

chromosomes condense, nucleus & cytoplasm divide

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2
Q

G1 Phase (gap)

A

interval between end of mitosis and beginning of S

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3
Q

S Phase (synthesis)

A

nuclear DNA replicated

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4
Q

G2 Phase

A

interval between end of S phase and beginning of mitosis

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5
Q

Interphase

A

G1+S+G2

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6
Q

G0

A

quiescence; cease dividing. then enter into S phase

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7
Q

How often does cell cycle happen?

A

every 12 hours in intestinal epithelial cell, once a year in liver cell, some cells exit cell cycle.

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8
Q

phases of mitosis

A

prophase, prometaphase, metaphase, anaphase, telophase, cytokenesis

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9
Q

prophase

A

chromosomes condense, not attached to mitotic spindle

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10
Q

prometaphase

A

nuclear envelope disassembled, mitotic spindle sends out microtubules, microtubules bind to kinetochore at centromeres and capture chromosomes

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11
Q

metaphase

A

chromosomes align along equitorial plate

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12
Q

anaphase

A

sister chromatid connections cut, one of each travel to opposite poles

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13
Q

telophase

A

nuclear envelope reassembles to form 2 daughter nuclei, chromos decondense into interphase state

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14
Q

G2/M Checkpoint

A

unreplicated DNA prevent entry to M phase (mitosis)

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15
Q

Spindle Checkpoint (aka Metaphase Checkpoint)

A

improper assembly of spindle leads to arrest in anaphase (chromosomes not lined up)

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16
Q

Restriction Checkpoint (G1 Checkpoint)

A

prevents entry into S phase until DNA damage repaired