Cell structure and functions Part 2 Flashcards

1
Q

Plant Cell walls

A
  • A protective layer external to and thicker than plasma membrane
  • Composed of microfibrils of cellulose secreted to extracellular space
  • Become embedded in matrix of other polysaccharides and proteins

Functions:

  • Protects and maintains shapes of cell
  • Prevents excessive water uptake
  • Holds plant up against gravity
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2
Q

Microfibrils

A

Long strings of cellulose bonded together by hydrogen bonds

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3
Q

Extracellular Matrix (ECM)

A
  • Made of glycoproteins and other carbohydrate-containing molecules secreted by cells
  • What connects cells to the membrane
  • Very important to keep human structure
  • Most abundant: collagen
  • Collagen fibres are embedded in proteoglycan network
  • Some cells are attached by firbonectin ( a glycoprotein)
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4
Q

Proteoglycan

A

Small core protein with any carbohydrate chains attached

  • Complexes form when many proteoglycans attach to one long polysaccharide molecule
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5
Q

Fibronectin

A

A ECM protein that binds to cell surface receptor proteins called integrins

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6
Q

Integrins

A
  • Built into ans span plasma membrane

Functions:

  • Bind microfilaments inside cell
  • Bind ECM outside cell
  • Transmit signals between ECM and cytoskeleton
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7
Q

Cell junctions

A

Cells need to adhere, interact and communicate with each other

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8
Q

Plasmodesmata

A
  • Perforations in plant cell walls, lined by plasma membrane
  • Channels connect cells so cytosol can pass through; this connection unifies most plants
  • Little holes within the cell walls to help the transmission and exchange of small nutrients between the cells
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9
Q

Main types of cell junctions

A
  1. Tight junctions
  2. Desmosomes
  3. Gap junctions

*Common in epithelial tissue that lines the outside or inside of body like ski, inside skin of mouth, external stomach tissue)

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10
Q

Tight junctions

A
  • Form continuous seals around the cells
  • Proteins make a tight seal to prevent the passage of water both in and out of cell
  • Present in stomach to keep acid in stomach; also present in skin
    Functions:
  • Prevent leakage of extracellular fluid across layer of epithelial cells
  • Prevent water of coming into cell
  • Stops our body from constantly losing water
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11
Q

Desmosomes

A
  • Have long intermediate filaments that hold the cell together and is hard to pull apart

Functions:

  • Function like rivets
  • Fasten cells together into strong sheets
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12
Q

Gap junctions

A
  • Provide cytoplasmic channels between cells
  • Similar to plasmodesmata
  • Ions and small molecules can through
  • Ions have a hard time passing through from other places because plasma membrane is mostly hydrophobic
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13
Q

Plasma membrane

A
  • 8nm thick
  • Controls traffic in and out of cell
  • Exhibits selective permeability (picky about what it lets in and out of cell)

Structure:

  • Phospholipds
  • Fluid mosaic model
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14
Q

Phospholipids

A
  • Most abundant lipids in most membrane
  • Ability to form membranes is inherent in their structure
  • Amphipathic (Both hydrophilic and hydrophobic –> hydrophilic head and hydrophibic tail)
  • Phospholipid bilayer
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15
Q

Fluid mosaic model

A
  • Currently accepted model of what plasma membrane is like in animal cells
  • Membrane is a mosaic of protein molecules drifting laterally in a fluid bilayer of phospholipids
  • they are constantly moving around because the bond is not very strong, only together because fatty acid tails want to avoid water
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16
Q

Membrane fluidity

A
  • Membranes are not static (Fluid mosaic model)
  • Some membrane proteins move, others do not
  • Affected by temperature –> if temperature decreases, phospholipids become packed together and membranes solidifies
  • Membrane with unsaturated hydrocarbon tails will remain fluid in lower temperature because kinds in tails prevent it from packing too closely
  • Presence of cholesterol )a steroid)
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17
Q

Cholesterol

A
  • a steroid
  • Wedged in between phospholipids in the plasma membrane of animals cells to act like a fluidity buffer
  • Helps maintain a certain fluidity and keeps it from becoming too spacious or too close
18
Q

What does membrane fluidity affect?

A
  • Permeability (what can come in or not)

- Ability of membrane proteins to move around

19
Q

Types of membrane proteins

A
  1. Integral proteins

2. Peripheral proteins

20
Q

Integral proteins

A
  • Penetrade hydrophobic interior of the lipid bilayer
  • Most are transmembrane (Span the entire membrane)
  • Some only extend partway into membrane
  • Hydrophobic regions have 1 or more streches of non-polar amino acids
  • Hydropilic parts exposed to aqueous solutions
  • Some have hydrophilic channels where hydrophilic substances can pass through (like a tunnel)
21
Q

Peripheral proteins

A
  • Not embedded in lipid bilayer
  • Appendages loosely bound to surface of membrane
  • Often exposed to parts of integral proteins

Placement:
- On cytoplasmic side (some attached to cytoskeleton)
- On extracellular side (attached to fibres of ECM)
Gives animal cells a stronger framework

22
Q

Major functions of protein

A
  1. Transport
  2. Enzymatic activity
  3. Signal diffusion
  4. Cell-cell recognition
  5. Intercellular joining
  6. Attachment to cytoskeleton and ECM
23
Q

Cell-cell recognition

A
  • Cells need to recognize one another

- Cells recognize other cells by binding to molecules on surface of membrane (often contain carbohydrates)

24
Q

Carbohydrates in cell-cell recognition

A
  • Short
  • Branched
  • If carbohydrate is covalently bonded to a lipid, it is called glycolipid
  • Carbohydrates covalently bonded to a protein is a glycoprotein
25
Q

Funtions of membranes

A
  • Membranes act as gatekeepers
  • Very selective
  • Substances move through membrane at different rates
26
Q

How do different substances pass through a membrane?

A
  • Hydrophobic substances pass through easily
  • Since interior is hydrophobic, hydrophilic substances have a harder time
  • Polar molecules pass very slowly
  • Charged molecules surrounded by water is even worse

Transport proteins help the substances pass quickly/easily

27
Q

Channel proteins

A

Transport protein

  • Hydrophilic channels through membrane
  • Acts like a tunnel

ex. Aquaporin

28
Q

Aquaporin

A

Type of channel protein

  • Helps water pas through membrane
29
Q

Carrier proteins

A

Transport protein

  • Hold onto their passenger and change shape to shuttle them across the membrane
  • Very specific of what it lets cross
  • Mostly only carry one type of substance
30
Q

Passive transport vs active transport

A

Passive: not required to input energy

  • Diffusion
  • Dynamic equilibrium (when concentration is equal on both sides of membrane)
  • Osmosis

Active: Requires energy

31
Q

Tonicity

A
  • Ability of a surrounding solution to cause a cell to gain or lose water
32
Q

Isotonic solution

A

Same concentration of non-penetrating solutes inside and outside of the cell

No net movement of water

In plant cells:
Cell becomes flaccid (limp)

33
Q

Hypertonic solution

A

Higher concentration of non-penetrating solutes

Cell loses water

In plant cells:
Cell loses water so plasma membrane pulled away from the wall

34
Q

Hypotonic solution

A

Lower concentration of non-penetrating solutes

Cell gains water

In plant:
Plant cell swells as water enters –> plant cell is tugid

35
Q

Plasmolysis

A
  • Plasma membrane pulls away from cell wall as cell shrinks in hypertonic environment
  • Causes plants to wilt and possibly die
  • Bacteria and fungi can also plasmolyze
36
Q

Facilitated diffusion

A
  • Passage of molecules or ions down their concentration gradient across a biological membrane down their concentration gradient across a biological memrane with the help of specific transmembrane proteins
  • Requires no energy
37
Q

Active transport

A

Uses energy to move solutes against their concentration gradient

  • From area of lower concentration to area of higher concentration
  • Energy is required
  • All of these transport proteins are carrier proteins
  • ATP supplies the energy

ex. Sodium-potassium pump that pumps ions against concentration gradients

38
Q

How are large molecules (like proteins and carbohydrates) transported across the membrane?

A

In bulk by being packed in vesicles

- Requires energy

39
Q

Exocytosis

A
  • Secretion of molecules by the fusion of vesicles from Golgi with the plasma membrane
40
Q

Endocytosis

A

Cell takes in molecules by forming new vesicles from plasma membrane

  • Membrane pinches inward while surrounfing molecules
  • Membrane buds off, forming a vesicle containing molecules

ex. Phagocytosis and pinocytosis are types of endocytosis