celldiffbrainscape Flashcards
(7 cards)
1
Q
examples of single cell migrations
A
gastrulation and neural crest migration
2
Q
snail represses these proteins and which results in loss of adherins and tight junctions
A
cadherin, claudins and occluding
3
Q
example of sequential induction
A
eye from 2 tissues, dorsal ventral of the neural tube
4
Q
describe TGF pathway
A
Type I and II receptors -> phosphorylate SMAD-> TF
5
Q
describe hedgehog pathway
A
patch inhibits smoothened->GLI cleaved by PKA and Slimb->cleaved GLI is TF repressoer
6
Q
describe Wnt pathway
A
wnt binds receptor->frizzled->disheveled->beta cantins ->nucleus->TF
7
Q
Describe nothc pathway
A
ligand binds extracellular doman->notch cleaved->notch enters nucleus->activated TF