Cells Flashcards

(87 cards)

1
Q

Cellular Projections

A

Not found in all cells, used for movement
Cilia moves materials across the cell surface
Flagellum propels the cell

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2
Q

Phospholipid Structure

A

A phospholipid molecule consists of a polar phosphate “head”, which is hydrophilic and non-polar lipid “tail”, which is hydrophobic. Unsaturated fatty acids result in kinks in the hydrophobic tails.

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3
Q

Phospholipid Bilayer

A

The phospholipid bilayer consists of two adjacent sheets of phospholipids, arranged tail to tail. The hydrophobic tails associate with one another, forming the interior of the membrane. The polar heads contact the fluid inside and outside of the cell.

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4
Q

Cell Membrane

A

The cell membrane of the cell is a phospholipid bilayer containing many different molecular components, including proteins and cholesterol, some with carbohydrates groups attached.

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5
Q

Simple diffusion across the call (plasma) membrane

A

The structure of the lipid bilayer allows only small non-polar substances such as oxygen and carbon dioxide to pass through the cell membrane, down their concentration gradient, by simple diffusion.

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6
Q

Facilitated Diffusion

A

Facilitated Diffusion of substances crossing the cell (plasma) membrane takes place with the help of proteins such as channel proteins and carriers proteins. Channel proteins are less selective than carrier proteins, and usually mildly discriminate between their cargo based on size and charge. Carrier proteins are more selective often only allowing one particular type of molecule to cross.

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7
Q

Osmosis

A

Osmosis is the diffusion of water through a semipermeable membrane down its concentration gradient. If a membrane is permeable to water, though not to a solute, water will equalize its own concentration by diffusion to the side of lower water concentration (and thus the side of higher solute concentration).

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8
Q

Hypertonic

A

solute concentration higher than another solution

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9
Q

Isotonic

A

solution has a solute concentration equal to another solution

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10
Q

Hypotonic

A

a solute concentration lower than another solution

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11
Q

sodium potassium pump

A

It is found in many cell (plasma) membranes. Powered by ATP, the pomp moves sodium and potassium ions in opposite directions, each against its concentration gradient. In a single cycle of the pump, 3 sodium ions are extruded from and 2 potassium ions are imported into the cell.
3 sodium (NA+): 2 potassium (K+)

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12
Q

endocytosis

A

Is a form of active transport in which a cell envelopes extracellular materials using its cell membrane.

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13
Q

Phagocytosis

A

which is relatively nonselective, the cell takes in a large particle

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14
Q

pinocytosis

A

the cell takes in small particles in fluid.

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15
Q

Receptor- mediated endocytosis

A

is quite selective, when external receptors bind a specific ligand, the cell responds by endocytosing the ligand

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16
Q

Exocytosis

A

Endocytosis in reverse. Material destined for export is packaged into a vesicle inside the cell. The membrane of the vesicle fuses with the cell membrane, and the contents are released into the extracellular space.

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17
Q

Smooth ER

A

synthesizes phospholipids, steroid hormones, regulates the concentration of cellular CA++, metabolizes some carbohydrates, and breaks down certain toxins

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18
Q

Rough ER

A

studded with numerous ribosomes, which are sites for protein synthesis

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19
Q

Golgi Apparatus

A

Manipulates products from the rough ER, and also produces new organelles called lysosomes. Proteins and other products of the ER are sent to the Golgi apparatus, which organizes, modifies, packages, and tags them. Some of these products are transported to other areas of the cell and some are exported from the cell through exocytosis.

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20
Q

Mitochondrion

A

They are the energy- conversion factories of the cell. A mitochondrion is composed of 2 separate lipid bilayer membranes. Along the inner membrane are various molecules that work together to produce ATP, the cell’s major energy currency.

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21
Q

Peroxisome

A

membrane bound organelles that contain an abundance of enzymes for detoxing harmful substances and lipid metabolism.

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22
Q

3 components of the cytoskeleton

A

consists of microtubules, microfilaments, and intermediate filaments. The cytoskeleton plays an important role in maintaining cell shape and structure, promoting cellular movement, and aiding cell division.

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23
Q

Nucleus

A

the control center of the cell, the nucleus of living cells contains the genetic material that determines the entire structure and function of that cell

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24
Q

multinucleate muscle cell

A

Unlike cardiac muscle cells and smooth muscle cell, which have single nucleus, a skeletal muscle cell contains many nuclei, and is referred to as “multinucleated”. These muscle cells are long and fibrous (often referred to as muscle fibers). During development, many smaller cells fuse to form a mature muscle fiber. The nuclei of the fused cells are conserved in the mature cell, thus imparting a multinucleated characteristic to mature muscle cells.

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25
Red blood cells extruding its nucleus
Mature red blood cells lack a nucleus. As they mature, erythroblasts extrude nucleus, making room from more hemoglobin.
26
DNA macrostructure
stands of DNA are wrapped around supporting histones. These proteins are increasingly bundles and condensed into chromatin, which is packed tightly into chromosomes when the cell is ready to divide.
27
Molecular structure of DNA
the double helix is composed of 2 complementary stands. The strands are bonded together via their nitrogenous base pairs using hydrogen bonds.
28
DNA replication
DNA replication faithfully duplicates the entire genome of the cell. During DNA replication, a number of different enzymes work together to pull apart the 2 strands so each strand can be used as a template to synthesize new complementary strands. The 2 new daughter DNA molecules each contain one preexisting strand and one newly synthesized strand. Thus, DNA replication is said to be "semiconservative".
29
The Genetic code
DNA holds all of the genetic information necessary to build a cell's proteins. The nucleotide sequence of a gene is ultimately translated into an amino acid sequence of the gene's corresponding protein.
30
Transcription
DNA to complementary mRNA
31
Splicing DNA
In the nucleus, a structure called a spliceosome cuts out introns (noncoding regions) within a pre-mRNA transcript and reconnects the exons.
32
Translation
RNA to protein, the mRNA transcript is "read" by a functional complex consisting of the ribosome and tRNA molecules. tRNA brings the appropriate amino acids in sequence to the growing polypeptide chain by matching their anti- codons with codons on the mRNA strand.
33
From DNA to protein: Transcription through translation
Transcription within the cell nucleus produces an mRNA molecule, which is modified and then sent into the cytoplasm for translation. The transcript is decoded into a protein with the help of a ribosome and tRNA molecule.
34
Cell cycle
2 major phases of the cell cycle include mitosis (cell division), and interphase when the cell grows and performs all of its normal functions. Interphase is further subdivided into G1, S, and G2 phases.
35
A homologous Pair of chromosomes with their attached sister chromatids
Each member of the pari was separately inherited from one parent. Each chromosome in the homologous pair is also bound to an identical sister chromatid, which is produced by DNA replication and results in the familiar "X" shape.
36
Cell division: Mitosis Followed by cytokinesis
the stages of cell division oversee the separation of identical genetic material into 2 new nuclei, followed by the division of the cytoplasm.
37
Control of the Cell Cycle
Cells produced through the cell cycle under the control of a variety of molecules, such as cyclins and cyclin- dependent kinases. These control molecules determine whether or not the cell is prepared to move into the following stage.
38
Hematopoiesis
The process of hematopoiesis involves the differentiation of multipoint cells into blood and immune cells. The multipoint hematopoietic stem cell give rise to many different cell types, including the cells of the immune system and red blood cells.
39
Stem cells
The capacity of stem cells to differentiate into specialized cells make them potentially valuable in therapeutic applications designed to replace damaged cells of different body tissues
40
Gene
DNA segment that carries a blueprint for building one protien
41
Protein synthesis
Proteins have many functions like being building materials for cells; or act as enzymes (biological catalysts), RNA is essential for protein synthesis
42
Body Tissues
Cells are specialized for particular functions also have similar structure and function, 4 types: Epthelium, connective, nervous, muscle
43
Epithelial Tissue
Functions: Protection, absorption, filtration, secretion Found in: Body coverings, body linings, glandular tissue Characteristics: cells fit together closely, tissue layer always has one free surface, the lower surface is bound by basement membrane, avascular, regenerate easily if well nourished
44
Simple
One layer
45
Stratified
many layers
46
Squamous
flattened
47
cuboidal
cube shaped
48
Columnar
column like
49
simple squamous
single layer of flat cells, usually forms membrane, lines body cavities found in LUNGS AND CAPILLARIES
50
Simple cuboidal
single layer of cube like cells, common in glands and their ducts found in WALLS OF KIDNEY TUBULES, COVERS THE OVARIES
51
simple columnar
single layer of tall cells, often includes goblet cells, which produce mucus found in LINING OF DIGESTIVE TRACT
52
Pseudostratified
single layer, but some cells are shorter than others, often looks like a double layer of cells, sometimes ciliated, may function in absorption or secretion found in RESPIRATOR TRACT
53
Stratified squamous
Cells at the fee edge are flattened, found as protective covering where friction is common found in SKIN, MOUTH, ESOPHAGUS
54
stratified cuboidal/ columnar
2 layers of cuboidal/ columnar cells, rare in the human body found mainly in DUCTS OF LARGE GLANDS
55
transitional epithelium
shape of the cell depends on the amount of stretching found in the LINING OF THE URINARY SYSTEM
56
Gland
one or more cells that secretes a particular product
57
Glandular epithelium
2 major gland types: endocrine and exocrine
58
Endocrine
Ductless, secretions are hormones
59
Exocrine
Empty through ducts to the epithelial surface, include sweat and oil glands
60
connective tissue
Found everywhere in the body, include the most abundant and widely distributes tissues Functions: Binds body together, supports the body, provides protection Characteristics: Variations in blood supply (some tissue is well vascularized and some are avascular/ poor blood supply) Extracellular matrix (non-living material that surrounds living cells)
61
Extracellular matrix
2 main elements ground substance and fibers
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Ground substance
mostly water along with adhesion proteins and polysaccharide molecules
63
fibers
Produced by the cells 3 types: collagen fibers, elastic fibers, and reticular fibers
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Bone (osseous tissue)
Composed of: Bone cells in lacunae (cavities), hard matrix of calcium salts, Large numbers of collagen fibers Used to protect and support the body
65
Hyaline Cartilage
Most common cartilage composed of: Abundant collagen fibers, Rubbery matrix Entire fetal skeleton is hyaline cartilage
66
Elastic cartilage
provides elasticity, supports the external ear
67
fibrocartilage
highly compressible, forms cushion like discs between vertebrae
68
dense connective tissue
Main matrix element is collagen fibers, cells are fibroblasts Ex: Tendons, ligaments
69
Tendon
attach muscle to bone
70
ligament
attach bone to bone
71
Areolar connective tissue
Most widely distributed connective tissue, soft pliable tissue, contains all fiber types, can soak up excess fluid
72
Adipose tissue
matrix is in areolar tissue in which fat globules predominate, many cells cantina large lipid deposits Functions: insulates the body, protects some organs, serves as a site of fuel storage
73
Recticular connective tissue
delicate network of interwoven fibers, forms stroma (internal supporting network) of lymphoid organs: lymph nodes, spleen, bone marrow
74
Blood
Blood cells surrounded by fluid matrix, fibers are visible during clotting Functions: the transport vehicle for materials
75
Muscle tissue
Function: produce movement Types: cardiac, skeletal, smooth
76
skeletal muscle
can be controlled voluntarily, cells attach to connective tissue, cells are striated, cells have more than one nucleus
77
cardiac muscle
found in HEART ONLY Functions: to pump blood (involuntary) cells attached to other cardiac muscle cells are intercalated disks, cells are striated, one nucleus per cell
78
Smooth muscle
involuntary muscle, surrounds hollow organs, attached to other smooth muscle cells, no visible striations, one nucleus per cell
79
Nervous tissue
Neurons and nerve support cells Function: send impulses to other areas of the body Irritability or conductivity
80
Regeneration
Replacement of destroyed tissue by the same kind of cells
81
Fibrosis
Repair by dense fibrous connective tissue (scar tissue)
82
Determination of method
type of tissue damage, severity of injury
83
Events in Tissue repair
Capillaries become very permeable (introducing clotting proteins, wall of injured area), formation of granulation tissue, regeneration of surface epithelium
84
tissues that regenerate easily
epithelial tissue, fibrous connective tissue and bone
85
Tissues that regenerate poorly
skeletal muscle
86
Tissues that are replaced largely with scar tissue
Cardiac muscle, nervous tissue within the brain and spinal chord
87
Developmental aspects of tissues
Epithelial tissues arise from all 3 primary germ layers, muscle and connective tissue arise from the mesoderm, Nervous tissue raised from the ectoderm, with old age there is a decrease in mass and viability in most tissues