Cells of the immune system

Question 1

Eosinophil (defense team)

Answer 1

is a granulated cell which releases its granules (Major Basic Protein) to attack parasites.

Question 2

Basophil (defense team)

Answer 2

contain cytoplasmic granules which it releases during inflammation and allergy responses

Question 3

Neutrophil (defense team)

Answer 3

are a phagocyte (cell eater) which circulates in the blood stream. These cells play a key role in innate immunity and inflammation.

Question 4

Macrophage (captain)

Answer 4

is a “big eater”. There are two main types, those that stay in the tissue to control infection and initiate local tissue repair, and those that are involved in inflammation and the initiation of the immune system.

Question 5

B cell (offense)

Answer 5

originate and are trained in the bone marrow. They will then move into the blood and secondary lymphoid organs. Once activated, they convert into Plasma cells and secrete antibody.

Question 6

T cell (offense)

Answer 6

are an important part of the adaptive immune response. They move from the bone marrow to the thymus for “training” and then released into the blood stream.

*80% of the lymphocytes in the blood will be these

Question 7

What are the 3 main types of T cells?

Answer 7

T helper cells, cytotoxic T cells, and regulatory T cells

Question 8

NK cells (natural killer) (offense)

Answer 8

are granulated lymphocyctes. They play a key role in the control of cancers and viral infected cells. In particular they respond to cells that are not behaving normally and have withdrawn a specific cell receptor called MHCI (normally present on all cells except RBCs). This causes them to release their granules to kill the cell.

Question 9

Hematopoietic Stem Cells are self renewing (T/F)?

Answer 9

True

Question 10

A Macrophage originates from which type of progenitor cell?

Answer 10

Myeloid

Question 11

Which cell is described here: This granulated cell is involved in inflammation and allergy responses?

Answer 11

Basophil

Question 12

This phagocytotic cell is a first responder as part of the innate immune system

Answer 12

Neutrophil

Question 13

Which cell is described here: This phagocytotic cell is able to command the involvement of the adaptive immune response?

Answer 13

Macrophage

Question 14

Which cell is described here: This granulated lymphocyte looks for cells that have withdrawn the MHCI cell receptor and then kills them?

Answer 14

Natural Killer Cell

Question 15

The numbers of the cells of the immune system are regulated by a process called “Hematopotetic homostatis”. What is the correct term for the cell death that occurs during this process?

Answer 15

Apoptosis

Question 16

The myeloid and lymphoid progenitor cells are capable of self renewal? T/F

Answer 16

False