Organ Review

Question 1

Is the site of hematopoiesis for all immune cells In humans, cats, dogs and mice*, ____ is the site of B-cells development where B cells proliferate and differentiate. Immature B cells are then tested to remove self-reactors. *Birds: B cell development in the bursa of Fabricius. Cattle and sheep: Spleen then Peyer’s patches

Answer 1

bone marrow

Question 2

is the site of T cell development and selection (cell death). Those animals that do not have a ____ will also not have the ability to induce cell-mediated immunity.

Answer 2

Thymus

Question 3

The thymus is made up of two distinict regions:

Answer 3

cortex and medulla

Question 4

The cortex of the thymus is densely packed with

Answer 4

immature T cells

Question 5

What are the 2 primary lymphoid organs?

Answer 5

bone marrow and thymus

Question 6

What are the 3 secondary lymphoid organs?

Answer 6

Lymph nodes, spleen, MALT and GALT

Question 7

What do the primary lymphoid organs do?

Answer 7

lymphocytes mature and are tested for self reactivity

Question 8

What do the secondary lymphoid organs do?

Answer 8

mature lymphocytes interact with antigens

Question 9

plays a major role in mounting immune responses to antigens present in the bloodstream. By filtering blood, it traps antigens and lymphocytes in circulation.

Answer 9

Spleen

Question 10

What are the 2 zones in the spleen?

Answer 10

Red Pulp and White Pulp

Question 11

What happens in the red pulp of the spleen?

Answer 11

there are a lot of Macrophage, RBC and a few lymphocytes. This is where old RBCs destroyed.

Question 12

What happens in the white pulp of the spleen?

Answer 12

the T lymphocytes surround the splenic artery and the B cells exist in follicles

Question 13

Are the sites where immune responses are mounted to antigens in the lymph fluid

Answer 13

lymph nodes

Question 14

are loosely structured clusters of lymphoid cells with large numbers of plasma (IgA antibody-producing) cells.

Answer 14

MALT

Question 15

Animals that lack a Thymus will also lack the ability to mount a cell-mediated immune response (T/F)

Answer 15

TRUE

Question 16

The cortex of the Thymus is where T cells interact with macrophage to determine if they are self-reactive.. (T/F)

Answer 16

FALE

Question 17

Which organ has M cells that sample the environment for pathogens?

Answer 17

MALT

Question 18

Which region of the lymph node would Plasma cells (B cells actively making antibodies) be found?

Answer 18

Medulla

Question 19

Which antibody type is associated with MALT?.

Answer 19

IgA