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Tissue Engineering > Cellular Fate Process & Signalling > Flashcards

Cellular Fate Process & Signalling Flashcards

1
Q

Cellular fate processes?

A 
Proliferation
Differentiation
Death
Migration
Adhesion
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2
Q

Migration types?

A

Chemotaxis
Haptotaxis (insoluble signal on surface)
Galvanotaxis (electrical signals)
Surface features (topography, contact inhibition)

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3
Q

Migration process?

A 
Extension (actin polymerisation)
Attachment (focal adhesion?)
Contraction forces (via myosin)
Release
Recycling
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4
Q

Factors affecting migration speed?

A

Ratio b/n contraction forces and substrate adhesion strength (function of substrate density and ligand affinity)

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5
Q

Cellular signalling ligand categories?

A

Diffusible molecules
ECM proteins
membrane-bound ligands

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Tissue Engineering (10 decks)

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