Central Dogma Flashcards

(34 cards)

1
Q

Helicase

A

The enzyme that breaks the h-bonds of the double helix

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2
Q

Topoisomerase

A

The enzyme that keeps the replication bubble open

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3
Q

The lagging strand

A

Fragments of DNA being made in the opposite direction of the replication bubble

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4
Q

Leading strand

A

the strand that is being made in the same direction as the repication bubble

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5
Q

DNA polymerase 3

A

Creates strands

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6
Q

DNA polymerase 1

A

Replaces RNA primer with DNA

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7
Q

DNA Ligase

A

Joins fagments

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8
Q

Okazaki Fragments

A

Fragments that make up the lagging strand

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9
Q

Primase

A

Creates the RNA that will be turned into DNA

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10
Q

What direction is DNA being made

A

from 5 prime to 3 prime

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11
Q

DNA replication

A

The process of creating two new identical strands of DNA

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12
Q

Cellular replication basic steps

A
  1. Copy DNA
  2. Separated the copies
  3. Divide cytoplasm
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13
Q

M phase check points

A
  1. Chromosome attached to spindle
  2. Chromosome separated
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14
Q

G2 check point

A

DNA replication finished

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15
Q

G1 check point

A

cell size, sufficient nutrients, undamaged

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16
Q

Interphase functions

A

cell growth, DNA duplicated, nucleus and organelles duplicated

17
Q

Gap phases purpose

A

allow cell to grow and replicate organelles

18
Q

Prophase

A

Chromosomes condense, spindles form

19
Q

Prometaphase

A

Nuclear envelop breaks down, microtubules contact chromosomes at center

20
Q

Metaphase

A

chromosomes move to middle of cell

21
Q

anaphase

A

sister chromatids separate

22
Q

telophase

A

new nuclear envelop formes and chromosomes de-condense

23
Q

Cytokinesis

A

cell division begins

24
Q

Plant cell spartation divider

25
Animal cell separation divider
cleavage furrow
26
cohesin
protein that holds sister chromatids together
27
Condensins
protein that compacts the DNA
28
Nuclear lamins
protein that stabilizes the nucleus
29
kinetochore proteins
attach microtubules to DNA
30
Origin of DNA replication
replication bubble
31
Direction of replication
5 prime to 3 prime
32
Replication basic steps (leading strand)
1. DNA is opened and primed 2. DNA polymerase 3 makes the leading strand
33
Replication basic steps (lagging strand)
1. RNA primer creates RNA replicates 2. first segment is synthesized 3. next fragment is synthesized 4. Primer is replaced with DNA by DNA polymerase 1 5. DNA ligase closes the gap
34
What enzyme repairs DNA
DNA polymerase