Cerebellum Flashcards
(50 cards)
Cerebellum function
- Correcting/preventing motor mistakes
- Ensuring accurate and smooth movements
- Associative learning system
- Role in cognition, language
Associative learning system
Learns to associate sensory input from actual movements with intended motor output (match motor output with expected sensory input).
–Contributes to learning new motor skills such as timing and coordination. Contributes to “automatic actions”
Vermis function
Midline movements
- Speech
- Posture
- Stance
- Gait
- Visceral function
Paravermis function
Appendicular movements
- Reaching
- Grasping
Lateral hemisphere function
Extensive reciprocal connections w/cortex
- Spatially and temporally complex movements needing coordination
- Cognition
Internal cerebellum structure
- Cortex
- White matter
- deep cerebellar nuclei
What are the deep cerebellar nuclei?
Dentate Interposed --Emboliform --Globus Fastigial
“Don’t Eat Green Frogs”
What deep cerebellar nuclei is the vermis associated with?
Fastigial
What deep cerebellar nuclei is the paravermis associated with?
Interposed (Emboliform and globus)
What deep cerebellar nuclei are the lateral hemispheres associated with?
Dentate
Cerebellar cortex function
Important for learning new movement combinations
White matter projections
Projections from the cortex to the deep nuclei
Deep cerebellar nuclei
Input: from cortex and direct input
Provide output from cerebellum
Ongoing movement monitoring
Purkinje cell layer
Perpendicular to the parallel fibers. Dendritic cells set up to receive information
How many contacts does each purkinje cell receive from parallel fibers?
10’s of thousands
Where do axons bifurcate from the granule cell layer? What are they called?
Molecular layer.
Parallel fibers
Mossy fibers
Massive in #.
Originate from wide variety of spinal and brainstem locations.
Excite: deep cerebellar nuclei and granule cells in cerebellar cortex.
Multiple mossy fibers synapse on each granule cell
Source of mossy fibers
Spinocerebellum
Vestibulocerebellum
Cerebrocerebellum
Spinocerebellum
Sensory and motor information from spinal cord.
Vestibular, auditory, and visual info
Vestibulocerebellum
Vestibular, auditory, and visual information
Cerebrocerebellum
Cerebral cortex (motor, sensory, prefrontal). Via pontine nuceli (not direct)
Inferior cerebellar peduncle
Ipsilateral input from dorsal and rostral spinocerebellar tracts and cuneocerebellar tract
Middle cerebellar peduncle
Massive contralateral input from pontine nuceli
Superior cerebellar peduncle
Mostly output. Input from ventral spinocerebellar tract
