Cerebellum, Cerebrum, Limbic system 2 Flashcards

(41 cards)

1
Q

True false - all tasks are bilaterally arranged in the cortex

A
  • FALSE, some are bilateral but many are unilateral
  • ex. lesion the non-fluent aphasia portion of the left hemisphere and have deficit, lesion same location on right hemisphere no deficit!
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

List two examples of bilateral tasks arrangement

A
  • hearing

- motor function (RLE on left side, LLE on right side)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What happens if bilateral lesion of parahippocampus? unilateral lesion?

A
  • bilateral: can’t make new memories

- unilateral: no problems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

when does lateralization of the brain occur?

A
  • early, it is reinforced by growth, development, and experience
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

symptoms of right parietal lobe lesions

A
  • hemineglect syndrome
  • ignore anything in left visual field: draw clock with all numbers on right side
  • almost exclusively after right lesions
  • loss of recognition of spacial relations
  • loss of prosody (ability o understand voice inflection, = monotone voice)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the two components of language function

A
  1. verbal - use and understanding of spoken, written, or read words (what you say), generally in the left cortex
  2. nonverbal - affective components such as inflection, intensity, emotion. Also called prosody, generally in teh right cortex
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

how much of the meaning of language is derived from prosody?

A

80-90%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the dominant language hemisphere for right handed people? left handed people?

A
  • Right handed: 96% left dominant, 4% right
  • left handed: 70% left dominant, 15% right, 15% both
    • Broca’s is located in dominant language hemisphere
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What happens if you lose Broca’s area?

what is this called?

A
  • can’t drive larynx, can’t speak
  • can understand written and verbal language
  • Broca’s aphasia, motor aphasia, or expressive aphasia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

If right handed and have a stroke of the left middle cerebral artery, what is most likely speech related deficit?

A
  • most people will have lost Broca’s area and won’t be able to speak
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What happens if a young child damages Broca’s area on the dominant side?

A

can develop a speech center on the opposite side (plasticity)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Split brain study:

- if cut corpus callosum what happens

A
  • right hemisphere knows what it is seeing
  • left brain can’t process what it is seeing
  • left hand can write what it sees (bc right brain knows what it is)
  • right hand can’t write what it is bc left brain never knew what it saw
    • he went over a bunch of other examples of this…
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How are Wernicke’s and Broca’s connected?

A
  • Wernicke’s interprets spoken language

- “tells” broca’s what to say in response to interpretation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What happens if Wernicke’s has a lesion

A
  • can hear what is said but can’t produce meaningful language
  • answer is completely wrong, words in wrong order
  • Wernicke’s aphasia or receptive aphasia
  • often do not know what saying is wrong
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
define;
difficulty speaking
inability to speak
difficulty in reading
inability to read
A
  • dysphasia
  • aphasia
  • dyslexia
  • alexia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Define:

  • apraxia

- agnosia

A
  • loss of task performance without loss of movement (agraphia)
  • loss of the significance of a sense: astereognosia, visual agnosia, auditory agnosia, amusia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Where is memory in the cortex

A

distributed widely

18
Q

types of memories (not classification)

A
  • auditory
  • visual
  • olfactory
  • procedural
19
Q

How are memories generated, how long do they last?

A
  • by experiences and practice

- can be fleeting or long lasting

20
Q

What structure “moves” memories from ST to LT

21
Q

re-written memories

A

add new information to a memory

22
Q

Two types of memory classification

A
  1. declarative (facts and events)

2. non declarative (procedural such as riding a bike, classical conditioning)

23
Q

What two brain structures can learn via classical conditioning?

A
  • cerebellum: pavlovs salvation

- amygdala: emotional conditioning, fear of a snake

24
Q

What brain structures are involved in procedural memory?

A

basal ganglia

25
What type of memory loss when lesion hippocampus bilaterally
anterograde, can't make new memories
26
Four Fs of limbic function
- fighting (aggression) - flight - feeding - fooling around * emotional/visceral brain
27
What is the role of the limbic system
- attach emotion to the moment | - determine physiologic response to the moment
28
What are the components of the limbic system (4)
- olfactory system - temporal lobe (parahippocampi and hippocampus) - amygdala - papez circuit
29
Overview of olfaction circuitry
- nerves through cribriform plate of the ethmoid bone - synapse in the olfactory bulb - project into the brain
30
Where do projections from the olfactory bulb go? Why is this significant?
- piriform cortex and entorhinl cortex - also amygdala * * straight to cortex without first synapsing in the thalamus, only sense to do this
31
What is sensitive about the circuitry of olfactory sensation?
sensitive to hypoxia | - temporal lobe epilepsy will often have an aura of a very unpleasant smell
32
Why is the hippocampus so sensitive to hypoxia?
- high metabolic rate | = memory is one of the first things to be lost after hypoxic events
33
Papez circuitry (9)
- cingulate cortex - cingulum - parahippocampal gyrus - hippocampus - fornix - mammillary bodies - mammillothalamic tract - anterior nucleus of thalamus - cingulate cortex
34
Lesion of the temporal lobe likely to cause what condition?
Alzheimer's | - related to ACh
35
Bilateral lesion of the amygdala causes what condition?
Kluver-Bucy syndrome
36
Kluver-Bucy syndrome sx
- flat affect - loss of learning - excessive exploratory behavior - hyperphagia - abnormal sexual behavior (mount everything)
37
Temporal lobe epilepsy sx
- aura of odor (orbital, frontal, entorhinal) - deja vu (hippocampus) - anxiety (amygdala) - rage (amygdala) - autonomic response
38
Dementia | - related to loss of what part of the brain
typically associated with lesions of the hippocampus
39
Four types of memory that can be lost
- anterograde: can't make new memories - retrograde: past memories - declarative: events that can be recalled, peoples names, faces - non-declarative: riding a bike, music, language
40
Wernicke's encephalopathy
- dysfunction/degeneration of mammillary bodies - assoc. with ethos abuse and lack of thiamine - confusion, memory loss, AMS, gate abnormality *thiamine before glucose
41
Korsakoff's syndrome
- etoh - amnestic confabulatory syndrome - fanciful realities - may visually hallucinate