Cerebral Cortex Flashcards

1
Q

What is the preferential site of excitatory synapses in pyramidal cells?

A

dendritic spines

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2
Q

What is special about dendritic spines?

A

suggested sites of synapses that are selectively modified as a result of learning
- small changes in spine configuration lead to electrical properties and in turn synapse efficacy

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3
Q

What do spiny stellate cells mainly receive?

A

most of afferent input from thalamus, other cortical areas

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4
Q

What do smooth stellate cells do?

A

silence weakly active cell columns in cortex (similar to focusing action noted in cerebellar cortex by Golgi cells)

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5
Q

Where are association fibers from?

A

long and short: from small and medium sized pyramidal cells in other parts of ipsilateral cortex

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6
Q

Where are commissural fibers from?

A

medium sized pyramidal cells via corpus callous or anterior commissure from corresponding contralateral cortex

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7
Q

Where are thalamocortical fibers from?

A

relay or association nuclei (VPL and VPM)

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8
Q

Where are non-specific thalamocortical fibers from?

A

intralaminar nuclei

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9
Q

Where are cholinergic and aminergic fibers from?

A

basal forebrain, hypothalamus (tuberoinfundibulum), brainstem (midbrain raphe, LC)

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10
Q

Where do efferent commissural fibers come from?

A

contralateral cerebrum via corpus callous and anterior commissure

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11
Q

What makes up the largest input to basal ganglia?

A

fibers from primary sensory and motor cortex

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12
Q

What receives input from all of the cortex?

A

thalamus

- corticopontine, corticospinal, corticobulbar

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13
Q

Association areas function?

A

mediate higher mental functions (language, art, music)

- not much known

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14
Q

What do the parvocellular layers of the eye detect?

A

layers 3-6 (color and form)

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15
Q

What do the magnoceelular layers of eye detect?

A

layers 1-2 (moment and contrast)

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16
Q

Which layers get input from contralateral eye? ipsilateral?

A

1,4,6

2,3,5

17
Q

What did Dr. Tatsuji describe?

A

retinotopic organization of primary visual cortex

18
Q

Where do optic radiations end?

A

retinotopically in occipital cortex, above and below calcarine sulcus

19
Q

Where do inferior visual fields end? superior?

A

superior above calcrine sulcus

inferior below calcimine sulcus

20
Q

How is the macula represented? peripheral fields?

A

most posteriorly, more anteriorly

21
Q

Where does primary visual cortex distribute info?

A

specialized parts of extra striate cortex

22
Q

How do columns in cortical modules analyze info?

A

visual field

- modules in foveal part analyze small areas so fovea has many more modules and therefore better resolution

23
Q

Which hemisphere is determined to be dominant?

A

one that produces and comprehends language (usually L)

24
Q

Where are the cortical language areas near?

A

lateral sulcus

25
What does the L lateral sulcus extend as making the hemispheres asymmetrical?
extends posteriorly as planum temporale
26
What happens if you stimulate the motor cortex near the mouth? other areas?
- produce involuntary grunts, vocalization | - cease to speak but can still move mouth or make linguistic errors
27
What is aphasia?
inability to use language, lose the use of or access to symbols humans use as concepts (words)
28
What interconnects Broca's and wernicke's areas?
arcuate (sup longitudinal fasciculus) | - damage wernickes leave broca's unchecked
29
What language is in the R hemisphere?
prosody = musical aspects of speech - R inf frontal gryrus produces prosody - R post temporoparietal region comprehends prosody
30
What is motor aprosody? sensory?
``` motor = can't convey authority, anger, etc in speech sensory = difficulty comprehending emotional content of speech from others ```
31
What areas are in parietal cortex?
- assoc areas post to primary somatosensory cortex | - unimodal areas: visual asso cortex, auditory assoc areas, somatosensory
32
What happens if damage parietal cortex areas?
agnosias: inability to recognize faces, perceive mvmt (visual agnosias)
33
Where are multimodal areas of parietal cortex?
centered on intraparietal sulcus, monitor relationships of body with outside world
34
Where is the prefrontal cortex? rule?
- frontal lobe ant to primary motor and supplemental motor cortices - controls activities of other cortical areas; underlies executive functions
35
What is the prefrontal cortex interconnected with?
dorsomedial nucleus of thalamus