Cervical lymph nodes and lymphadenopathy Flashcards
What are the roles of the lymphatic system?
Remove excess tissue fluid
Return small proteins and fluid leaked from capillary
Immune defence & Surveillance - source of lymphocytes, physical barrier
What is lymphoedema?
Accumulation of tissue fluid
Usually in lower/upper limbs
What is lymphadenopathy?
Enlarged lymph nodes due to infection or malignancy (can be metastases or primary lymphoma)
common in neck
Why do pathologies sometimes lead to more than one lymph node being involved?
All material transported by lymph usually passes through AT LEAST 1 node before reaching venous circulation
This means things can spread via lymph
Types of filtering in lymph and what this can lead to
Physical filter
Phagocytic filter
Full of T and B lymphocytes - if proliferate can lead to enlargement
Regions where lymph nodes can be palpated
Neck
Groin
Axilla
some nodes even when enlarged cannot be palpated. some can be palpated even when not enlarged
What is Waldeyers ring?
Annular collection of lymphoid tissue (NOT NODES) surrounding the upper aerodigestive tract
Tonsils that make up Waldeyers ring
Pharyngeal tonsil/adenoids (top of nasopharyngeal area)
Tubal tonsil (just below)
Palatine tonsil (the ones we see and refer to)
Lingual tonsil (under posterior tongue)
Problem with enlargement of pharyngeal tonsil/adenoids
Common in children
Obstruction of nasal breathing - snoring/mouth breathing
Blockage of eustachian tube (leading to middle ear problems)
What is common cause for neck lump in children and adults?
Lymphadenopathy
In most cases, is lymphadenopathy a cause for concern?
No, most cases benign and self limiting caused by local infection of tissues drained by that lymph node
When should you be concerned about lymphadenopathy?
Risk of concern rises with age. Older you are = more likely to be something serious
Palpation findings for reactive (due to infection) lymphadenopathy
Tender
Mobile - does not feel stuck to tissues
Recent rapid enlargment
+ History suggests infective cause
Two reasons for lymphadenopathy
Reactive - infection
Malignancy
Palpation findings for secondary malignancy in node (metastases)
Hard - rock like
Tethered to surrounding tissues
Painless palpation
Palpation findings for primary malignancy eg lymphoma
Rubbery
Painless to palpate
Fast-growing
History from pt which suggests malignant cause for lymphadenopathy - Red flags
Weight loss
Night sweats
Persisting >6 weeks
Fixed, hard and irregular
Rapidly growing
Generalised lymphadenopathy (across body)
Unexplained change in voice/hoarseness or difficulty swallowing
Other places to palpate when pt comes in with lymphadenopathy
Spleen
Other palpable areas eg groin, neck and axilla