Ch. 13 - Sexually Transmitted Bacterial Diseases Flashcards Preview

Microbiology > Ch. 13 - Sexually Transmitted Bacterial Diseases > Flashcards

Flashcards in Ch. 13 - Sexually Transmitted Bacterial Diseases Deck (15):
1

Pelvic Inflammatory Disease (PID)

Inflammation of uterus, ovaries, Fallopian tubes

Pouches and adhesions

2

Bacterial vaginosis

Caused by indigenous bacteria of vagina

Switch from dominance of lactobacillus to others

Common vaginal infection

3

Gonorrhea (the clap!)

Neisseria gonorrheae

Gram negative diplococcus

Major virulence factor - pili --> attach to host epithelial cells

Characteristic double bean shape

Gonococcal urethritis plus non-urogenital organs

Neonatal conjunctivitis --> gonococcal opthalmia -->through birth canal

Symptoms: painful urination, discharge (thick, viscous), salpingitis

Treatment: ceftriaxone

4

Gonorrhea - female

Salpingitis - blocked and inflamed Fallopian tubes

Pelvic Inflammatory Disease

Ectopic pregnancy

Possible sterility

Often asymptomatic

5

Chlamydia urethritis

Chlamydia trachornatis - gram negative rod, obligate intracellular parasite (in WBC)

Biphasic life cycle: non-replicating extracellular infectious body; replicating intracellular non-infectious body

Non gonococcal urethritis (NGU)

85-90% people asymptomatic --> Silent Disease

Symptoms: painful urination, watery discharge, salpingitis

Treatment: doxycycline, erythromycin

6

Chlamydia - females

Asymptomatic until salpingitis

Untreated leads to PID

Increased danger of infertility or ectopic pregnancy

7

Chlamydia - males

Painful urination

Watery discharge

Inflammation of epididymis --> sterility

8

Syphilis (the great pox)

Treponema palladium - gram negative spirochete (humans only host)

Penetrate skin surface via wound, abrasion, hair follicle (via flagella)
Lack of outer membrane proteins - invisible to immune system

Symptoms: chancre (primary), skin lesions, Gumma (tertiary)

Treatment: penicillin --> early stages (primary or secondary)

9

Primary Syphilis

Chancre (hard) where bacteria entered body

Painless, circular, purple ulcer

Hard borders

10

Secondary Syphilis

The great imitator -- variety of physical symptoms

Spirochete so spread through body and lymph to other organs

Fever, skin rash, swollen lymph nodes

Latent state --> 3-30yrs later; relapse of secondary syphilis

11

Tertiary Syphilis

Chronic

Formation of gummas cause:
-bursting of blood vessels
-degeneration of spinal tissue
-brain damage --> changes in personality

12

Congenital Syphilis

In fetus - cross placental barrier after 4th mo.

Lead to stillbirth

Birth defects: Hutchinson's Triad (deafness, blindness, notched teeth)

13

Chranchoid

Haemophilus ducreyi - Gram negative rod

Soft chancre - painful, genital ulcers; soft borders; forms at entry site

Fills with pus - open wound -- transmission via contact
More susceptible to other STDs, AIDS

Symptoms: soft chancre, erythema, swollen inguinal lymph nodes

Treatment: azithromycin, erythromycin, ceftriaxone

Men - lesions on penis painful
Women - lesions on labia, clitoros unnoticed

Disappear 10-14 days without treatment

14

Gonorrhea - males

Painful urination

Penile discharge - thick, viscous

Swollen groin lymph nodes --> painful testes

Infertility - infection in epididymis

15

Urinary Tract Infection

Kidney, bladder, ureter = sterile

Urethra = indigenous microbiota (shorter in women, more common ascending into bladder)

E. Coli primary cause

Urethritis - inflammation of urethra; pus, painful urination

Cystitis - infection of bladder

Pyelonephritis - kidney infection; lower back pain

Prostitis - prostate infection; increased urination, fever, chills

Treatment: sulfa drugs, Bactrin (combo of sulfa drugs)