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Flashcards in Ch. 14 Book Questions + Class ?s Deck (18)
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The facial nerve (cranial nerve VII) supplies muscles derived from which pharyngeal arch?
a. First
b. Second
c. Third
d. Fourth
e. Sixth

b. Second


Cleft lip results from lack of fusion of the:
a. Nasomedial and nasolateral processes
b. Nasomedial and maxillary processes
c. Nasolateral and maxillary processes
d. Nasolateral and mandibular processes
e. Nasomedial and mandibular processes

b. Nasomedial and maxillary processes


In cases of holoprosencephaly, defects of facial structures are typically secondary to defects of the:
a. Pharynx
b. Oral cavity
c. Forebrain
d. Eyes
e. Hindbrain

c. Forebrain


Meckel’s cartilage is a prominent structure in the early formation of the:
a. Upper jaw
b. Hard palate
c. Nasal septum
d. Soft palate
e. Lower jaw

e. Lower jaw (mandible)


An early induction in tooth development consists of the ectoderm of the dental epithelium acting on the underlying neural crest mesenchyme. Which of the following molecules is an important mediator of the inductive stimulus?
a. BMP-4
b. Tenascin
c. Hoxb-13
d. Msx-1
e. Syndecan

a. BMP-4


Except for musculature, all the rest of pharyngeal arch mesenchyme (especially ventral) is derived from:
a. somitomeres
b. mesoderm
c. neural crest
d. ectoderm

c. neural crest

Pharyngeal arch derived musculature: mesoderm from somitomeres


The segmentation of cranial neural tube occurs as a result of what gene expression?
a. Otx-2
b. FGF-8
c. BMP-4
d. Hox

d. Hox


What pair is involved the establishment of a dorsoventral gradient and in the shaping of the tip of the snout?
a. FGF-8 and Shh
b. FGF-8 and BMP-4
c. BMP-4 and Shh
d. Hox and Shh

a. FGF-8 and Shh


Which precursor becomes the malleus?
a. Meckel's cartilage
b. Quadrate
c. Articular
d. Reichert's

c. Articular


At what stage do ameloblasts and odontoblasts first appear?
a. Dental lamina
b. Tooth bud
c. Cap stage
d. Bell stage
e. Dental sac

d. Bell stage


Which of the following is necessary for tooth development to continue past the bud stage?
a. Pax-9
b. BMP-4
c. Msx-1
d. FGF-8
e. Shh

a. Pax-9


Which of the following occurs under the influence of the secondary enamel knots?
a. regression of primary enamel knot
b. the future cusps of the molar begin to form
c. inductive proliferation of Lef-1
d. creation of non-tooth-forming spaces

b. the future cusps of the molar begin to form


A patient presents with teeth that appear blue-gray or amber brown and are opalescent and has a mutation in Type I collagen. What is the diagnosis?
a. Dental fluorosis
b. Amelogenesis imperfecta
c. Microdontia
d. Dentinogenesis imperfecta

d. Dentinogenesis imperfecta


From which pouch is the auditory tube derived?
a. first
b. second
c. third
d. fourth

a. first

second - fossa for palatine tonsils
third - inferior parathyroids & thymus
fourth - superior parathyroids & postbranchial (ultimobranchial) body


What is a derivative of the third pouch and forms in response to high concentrations of Shh?
a. Thymus
b. Tonsils
c. Inferior parathyroids
d. Superior parathyroids

c. Inferior parathyroids


These cells become incorporated into the thyroid as parafollicular (C) cells which secrete calcitonin and are derived from which pouch?
a. first
b. second
c. third
d. fourth

d. fourth


What does Rathke's pouch become?
a. thyroid
b. adrenal hypophysis
c. tongue
d. tonsils

b. adrenal hypophysis


In mutations of the TCOF1 gene, neural crest cell migration is normal, but increased apoptosis and decreased proliferation result in a much reduced population of neural crest cells in the first pharyngeal arch, resulting in hypoplasia of the mandible and facial bones, malformations of the external and middle ears, high or cleft palate, faulty dentition, and coloboma-type defects of the lower eyelid. What is this condition?
a. Micrognathia
b. Pierre-Robin
c. Treacher Collins syndrome
d. Ankyloglossia
e. DiGeorge's

c. Treacher Collins syndrome