Ch 16 Endocrine System Flashcards

1
Q

What hormones are secreted by the thyroid gland?

A

T3, T4, calcitonin

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2
Q

What produces T3 and T4?

A

follicular cells

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3
Q

What produces calcitonin?

A

parafollicular cells

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4
Q

What is thyroid deficiency in a fetus called?

A

cretinism

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5
Q

What is hypothyroidism?

A

hyposecretion of T4 and T3

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6
Q

What is severe or prolonged adult hypothyroidism called?

A

myxedema

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7
Q

What does hypothyroidism produce in adults?

A
  • sensitivity to cold/low body temp.
  • constipation
  • weight gain
  • thick/dry skin & puffy eyes
  • lethargy/myalgias/hypoactive reflexes
  • low heart rate
  • mental dullness/ memory impairment/ depression
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8
Q

Hyperthyroidism

A

hyper metabolic state secondary to increased thyroid hormone levels

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9
Q

Grave’s disease

A

autoimmune disease with weight loss, nervousness, irregular heart beat, sweating, tremor & exophthalmos(edema behind eyes)

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10
Q

Goiter

A

enlarged thyroid gland

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11
Q

Calcitonin

A

secreted by the parafollicular cells in the thyroid gland

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12
Q

What stimulates the release of calcitonin?

A

high blood calcium levels

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13
Q

Hyperparathyroidism

A

usually caused by a parathyroid gland tumor

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14
Q

Hypoparathyroidism

A

usually caused by trauma to parathyroid gland, surgical removal, or autoimmune processes

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15
Q

Aldosterone

A
  • secreted by adrenal cortex
  • stimulated by hyperkalemia, hyponatremia, angiotensin II
  • targets kidney
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16
Q

Hyperaldosteronism (Conn’s disease)

A

too much aldosterone secreted, hypokalemia

17
Q

Hypoaldosteronism (Addison’s disease)

A

not enough aldosterone secretion, hyperkalemia

18
Q

Cortisol

A

-secreted by adrenal cortex
-stimulated by patters of eating and activity, peaks after getting up in morning, stress
targets protein breakdown, gluconeogenesis, lipolysis

19
Q

Cushing’s Syndrome

A

-excessive amounts of glucocorticoids
-signs and symptoms:
hyperglycemia, moon face, buffalo hump, easy bruising, poor wound healing

20
Q

Addison’s Disease

A

deficient amounts of glucocorticoids & aldosterone

21
Q

Pheochromocytoma

A

excessive amounts of catecholamines secreted into blood

- usually cause by a tumor of adrenal medulla

22
Q

Type I Diabetes Mellitus

A
inadequate or no insulin secretion
- cardinal symptoms
polyuria
polydipsia
polyphagia
23
Q

Type II Diabetes Mellitus

A

problem in cell signaling cascade, inadequate/ineffective insulin secretion, decreased numbers/effectiveness of insulin receptors, insufficient/ineffective glucose transporters, too much resistin hormone, OR too much liver output of glucose