CH 28 - pregnancy and human development Flashcards
(29 cards)
gestation period
time from last mens to birth
acrosomal reaction
sperm reaches zona pellucida causing ca channels to influx into the sperm, sperm then release enzymes that creates hole in the zona pellucida
in humans is it polyspermy or monospermy
monospermy - only one sperm penetrates oocyte
what ensures our monospermy?
OOcyte membrane block = other sperm binding receptors are shed
Zona reaction = entry of sper –> Ca surge –> Cortical reaction = ZIP enzymes destroy zona pellucida sperm binding receptors
what happens after sperm penetrates oocyte
oocyte completes meiosis II
sperm and ovum swell –> pronuclei
pronuclei replicate and mitosis begin
Zygote to Blastocyst
- Cleavage = zygote divides rapidly as it moves toward uterus, producing 2 daughter cells called blastomeres –> morula
- Blastocyst formation = embryo consisting of many cells is now called blastocyst as it reach uterus
cells in blastocyst
trophoblast = immunosuppresive, placenta formation, form 4th extraembryonic membrane (chorion)
embryoblast = for extraembryonic membranes
cytotrophoblast vs syncytiotrophoblast
cytotrophoblast = becomes “inner” layer of cells surrounding embryoblast
syncytiotrophoblast = digest endometrium lining of uterus
what prevents menstruation and shows that one is pregnant
human chorionic gonadotrophin (hCG)
what secrets human gonadotrophin
trophoblast cells and later chorion (which is released by trophoblast cells)
formation of placenta
originate from both embryonic and maternal tissues
Baby = inner cells and trophoblast form chorion –> chorionic villi + blood vessel –> umbilical cord
Mom = uterus breaks down a bit –> makes blood pool called lacunae –> allows it to pick up nutrients
what makes up placenta
baby’s chorionic villi + mom’s decidua basalis
decidua basalisdecidua capsularis
part of placenta that expand to accomodate growth –> villi also degenerate as fetus grow
T or F placenta secretes hCG from beginning until production of estrogen and progesterone increase
True
Why are some pregnancy not viable
if placental hormone (estrogen and progesterone) are not enough when hCG levels begin to go down, endometrium starts degenerating
Extraembryonic membrane (amnion)
sac filled with amniotic fluid enveloping the embryo
Yolk sac (extraembryonic membranes)
source of earliest blood cells
form part of digestive tube
allantois (extraembryonic membranes)
end of yolk sac
base of umbilical cord
become part of urinary bladder
notochord
formed from aggregation of mesoderm that serve as first axial support of embryo
ectoderm becomes
nervous system and skin
endoderm becomes
lining of digestive, respiratory ad urogenital systems and associated glands
umbillical arteries
cary deoxygenated blood from fetus to placenta (away from baby)
umbillical vein
carry oxygenated blood to fetus
human placental lactogen (hPL) or human chorionic somatomammotropin (hCS)
stimulate maturation of breasts, fetal growth and glucose sparing