Ch 38 Flashcards
What drugs inhibit cell wall synthesis
Cephalosporins
Daptomycin
Penicillins
Vancomycin
What drugs inhibit protein synthesis
Aminoglycosides Chloramphenicol Clines yin Erythromycin Tetracyclines
What drugs inhibit nuclei acid synthesis
Fluoroquinolones
Rifampin
What drugs disrupt cell membrane permeability
Polymyxins
Polynesia antimicrobials
Imidazole antifungal agents
What drugs work as an anti metabolite
Sulfonamides
Trimethoprim
What drugs inhibit viral enzymes
Acyclovir saquinavir
What does fluoroquinolones do
They inhibit deoxyribonucleic acid (DNA), an enzyme needed for bacterial replication
Anti metabolites
Inhibition of metabolic pathways
What is nuclei acid synthesis dependent on
Folic acid
What do sulfonamides do
They inhibit bacterial folate synthesis by acting as an anti metabolite
What is the drug of choice for MRSA and MRSE
Vancomycin
What is the pharmacotherapuetics of vancomycin
Treating bacterial septicemia, endocarditis, bone and joint infections
Treatment of MRSA, D-DIFF, PNEUMONIA AND STPAHYLOCOCCAL INFECTIONS
What are adverse effects of vancomycin
Red neck or red mans syndrome…..infuse at least over 60 min to avoid the syndrome
Nausea, vomiting, stomatitis
Nephrotoxicity ( BUN greater than 8-18) assess 4 cloudy or pink urine ( nephrotoxicity)
IV site irritation with tissue necrosis
What are nursing diagnosis for vancomycin
Risk for injury R/T drug induced histamine release reactions
Disturbed sensory perception ( auditory) R/T drug induced Ototoxicity
Excessive fluid volume R/T nephrotoxicity fro drug therapy
What are ongoing assessments of vancomycin
Monitor for signs of Ototoxicity
Coordinate periodic audiometric testing and lab tests
Explain the need for periodic blood monitoring
