Ch 27 Urinary Output Flashcards

0
Q

What is a creatinine lab

A

Diagnostic test that truly tells how well the kidney are functioning

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1
Q

How much urine does the kidney need to produce before they start to shut down

A

At least 30 ml hour

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2
Q

What is osmolality

A

The strength or concentration of the urine produced

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3
Q

What does the renal system consist of

A

Kidneys

Ureter and bladder

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4
Q

What is one reason for kidney failure

A

Long standing diabetes

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5
Q

What drugs are used in treating fluid overload or edema

A

Diuretics

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6
Q

What conditions does diuretics treat

A
Chronic heart failure
Pulmonary edema
HTN
Cirrhosis ( liver failure)
Nephrotic syndrome
Kidney failure
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7
Q

What is the prototype drug of thiazide diuretics

A

Hydorchlorothiazide ( HydroDIURIL)

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8
Q

What are thiazide diuretics used for

A

In the treatment of hypertension

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9
Q

Where does thiazide diuretics work

A

In the distal tubule

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10
Q

What are contraindications and precautions of thiazide diuretics

A

Severe renal impairment
Anuria
Hepatic coma
Hypersensitivity

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11
Q

What are adverse effects of thiazide diuretics

A
Hypokalemia 
Hyponatremia 
Hypochloremia
Hypomagnesemia
HYPERCALCEMIA
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12
Q

What drug does thiazide diuretics interact with

A

Digoxin

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13
Q

With any diuretic what should you monitor for

A

Hypokalemia

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14
Q

What is a contraindication to thiazide diuretics

A

Sulfa

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15
Q

What are signs and symptoms of hypokalemia

A

Arrhythmias

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16
Q

What is a sign of hyponatremia

A

The body craving salt

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17
Q

Hydrochlorothiazide is more effect in what ethnic group

A

African Americans

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18
Q

What is a loop diuretic

A

They excerpt a powerful effect on fluid and electrolyte balance
They work in the loop of henle to inhibit sodium and chloride

19
Q

What are loop diuretic used for

A

Pulmonary edema
CHF
Peripheral edema
it depletes K+ very fast

20
Q

What is the prototype drug of loop diuretics

A

Furosemide ( lasix)

21
Q

How are loop diuretics administered

A

IV or oral

Excreted in the kidneys

22
Q

What are adverse effects of loop diuretics

A

Electrolyte imbalance
Ototoxicity if pushed too fast
Alteration in blood glucose levels
Alecia man

23
Q

What 2 drugs shouldn’t be given concurrently with loop diuretics

A

Digoxin

Aminoglycosides

24
How long should one push furosemide
20-40 mg over 1-2 minutes | Closely monitor potassium levels
25
What labs should be monitored with furosemide
CBC SERUM ELECTROLYTE URIC ACID LEVELS
26
Wh would a pt who is malnourished be at greater risk for toxicity from furosemide
Because the malnourished pt has less protein in the body which will result in more free drug. Furosemide is a highly protein bound drug
27
Potassium sparing diuretics prototype drug
Triamterene ( Dyremium)
28
What are potassium sparing diuretics used for
It is used as an adjunct to manage edema and HTN
29
What is indomethacin used for
It is an anti inflammatory that treats gout
30
What are adverse effects of triamterene ( Dyrenium) | Potassium sparing diuretic
``` Hyperkalemia Nephrotoxic it's Thrombocytopenia Elevated liver enzymes Headache Photosensitivity ```
31
What lab level indicates thrombocytopenia
Platelet count less than 50,000
32
What are normal platelet counts
150,000-450,000
33
What are osmotic diuretics used for
They are used for intracranial pressure & pushes fluid back into vascular space Cerebral edema And reduces intraocular pressure It causes a severe electrolyte imbalance it is a very strong diuretic
34
What is the only way that mannitol is administered
IV
35
What is a test to determine how well the renal system is functioning
GFR
36
The bigger the dilation of a persons pupils are a indicator of what
You are going to die! | Coma is occurring
37
What are contraindications and precautions of mAnnitol (osmotic diuretic)
Severe renal disease Pulmonary congestion Active intracranial bleeding
38
What are adverse effects of osmotic diuretics ( mannitol)
Fluid or electrolyte imbalances Hypotension Tachycardia
39
What are major drug interactions of mannitol ( osmotic diuretic)
NONE
40
How can one maximize the therapeutic effects of mannitol
Know than concentrations that exceed 15% have a tendency to crystallize. An inline filter should be used for the infusion
41
How can one minimize the adverse effects of mannitol( osmotic diuretic)
``` Monitor hourly output 30-50 ml/ hr at least Monitor BP pulse rate Electrocardiographic tracings Intake to output ratios Renal function test results Serum electrolyte levels ```
42
How should mannitol be administered
Parenterally | .2g over 3-5 min in 2 doses
43
What is mannitol administered for
Cerebral edema | Increase intraocular pressure
44
Sodium bicarbonate
ABGs | Base