CH. 51 Acute Coronary syndromes

Question 1

Symptoms of ACS

Answer 1

chest pain, dyspnea, syncope or lightheadedness, diaphoresis (sweating)

Question 2

Risk factors for ACS

Answer 2

age men >45 and women > 55, family history, smoking, hypertension, dyslipidemia, diabetes, chronic angina, known coronary artery disease, lack of exercise, excessive alcohol

Question 3

Nemonic for ACS

Answer 3

MONA-GAP-BA

Question 4

Type of glycoprotein IIb/IIIa receptor antagonists?

Answer 4

abciximab, eptifibatide or tirofiban

Question 5

Types of P2Y12 inhibitors

Answer 5

clopidogrel, prasugral and ticagrelor

Question 6

Which 2 P2Y12 inhibitors are prodrugs?

Answer 6

clopidogrel, prasugral

Question 7

Contraindication with prasugral?

Answer 7

hx or TIA or stroke

Question 8

When to you prasugral?

Answer 8

ACS who are to be managed with PCI

Question 9

Effient

Answer 9

prasugrel

Question 10

Brillinta

Answer 10

ticagrelor - reversible

Question 11

Kengreal

Answer 11

cangrelor

Question 12

ReoPro

Answer 12

abciximab - irreversible

Question 13

Integrillin

Answer 13

eptifibatide

Question 14

Aggreastat

Answer 14

tirofiban

Question 15

With ticagrelor what is the maintenance dose for ASA?

Answer 15

<100 mg

Question 16

What is the first dose of ASA when the patient comes to the hospital?

Answer 16

325 mg

Question 17

which P2Y12 is injectable?

Answer 17

cangrelor

Question 18

MOA of fibrinolytics?

Answer 18

bind to fibrin in clot and converting entrapped plasminogen to plasmin.

Question 19

When are fibrinolytics used for?

Answer 19

only STEMI

Question 20

What is the door to needle time for fibrinolytic?

Answer 20

30 minutes (ASAP)

Question 21

what is the door to balloon time for PIC?

Answer 21

90 minutes

Question 22

Types of fibronolytics?

Answer 22

alteplase, tenecteplase, reteplase

Question 23

Activase

Answer 23

alteplase

Question 24

TNKase

Answer 24

tenecteplace

Question 25

Retavase

Answer 25

reteplase

Question 26

MOA of vorapaxar?

Answer 26

protease-activated receptor-1 antagonist

Question 27

Zontivity

Answer 27

vorapaxar

Question 28

Long term aspirin use?

Answer 28

81 mg indefinitely

Question 29

long term P2Y12 inhibitor use?

Answer 29

12 months

Question 30

long term nitrate use?

Answer 30

tabs or spray as needed

Question 31

long term BB use

Answer 31

3 years or longer if needed for other disease states

Question 32

target HR for BB

Answer 32

50-60 BPM

Question 33

long term ACE use?

Answer 33

indefinitely if reduced EF, HTN, CKD, DM

Question 34

long term aldosterone antagonist use?

Answer 34

indefinitely if HF, DM

Question 35

long term statin use?

Answer 35

indefinitely b/c clinical ASCVD