ch10pt2 Flashcards

(37 cards)

1
Q

neural stimulation of sarcolemma (skeletal muscle contraction) causes

A

excitation-contraction coupling

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2
Q

action potential travels along _-___ to __

A

t-tubules, SR (sarcoplasmic reticulum)

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3
Q

______ is released from SR via ___ ___ ___ _______

A

calcium, voltage gated ion channels

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4
Q

_______ binds to _____, causing tropomyosin to uncover the ____ ____ on actin

A

calcium, troponin, active site

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5
Q

interaction between thick and thin filaments causes the muscle to

A

contract

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6
Q

Contraction of many muscle fibers produces ____ in the muscle

A

tension

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7
Q

intercellular connection between the nervous system and skeletal muscle fiber

A

neuromuscular junction (NMJ)

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8
Q

____ ____ (electrical stimulus) is transferred from neuron to the muscle fiber via a _____

A

action potential, neurotransmitter

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9
Q

Area where calcium ions release onto the sarcolemma

A

neuromuscular junction

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10
Q

type of motor neuron controlling skeletal muscles

A

somatic motor neurons

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11
Q

stretches from neuron to muscle

A

axon

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12
Q

end of each axon branch

A

synaptic terminal

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13
Q

One axon and all the fibers it stimulates

A

motor unit

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14
Q

Action potential stimulates ___ __ ____ of the fibers in a motor unit

A

all or none

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15
Q

Small motor units give _______ control

A

fine

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16
Q

Large motor units give _________.

17
Q

neurotransmitter used to pass signal from neuron to muscle fiber

A

acetylcholine

18
Q

a narrow space separating the synaptic terminal of the neuron from the opposing motor end plate

A

synaptic cleft

19
Q

enzyme which breaks down acetylcholine (ACh). present in synaptic cleft

A

acetylcholinesterase (AChE)

20
Q

When the action potential reaches the neuron’s synaptic terminal, it triggers the exocytosis of ___ into the ________ _____.

A

acetylcholine (ACh), synaptic cleft

21
Q

ACh diffuses across the
synatpic cleft and binds
to ACh receptors on the
_____ ___ _____. ACh
binding opens ligand-gated
sodium channels. Na+ ions rush into the ___________.

A

motor end plate, sarcoplasm

22
Q

Action potential reaches a triad
Releasing Ca2+ , uncovering active sites on Actin, allowing Actin and Myosin interaction

A

excitation-contraction coupling

23
Q

Interaction between Actin and Myosin. Shortening of the Sarcomere.

A

cross bridge cycle

24
Q

must be present in order to free up active sight on actin

25
shortening of sarcomere (cross bridge cycle) requires myosin heads to be in "_______" position
cocked
26
___ loads myosin heads into ____ position, therefore requiring energy
ATP, cocked
27
ATP turns to ___ in order to free up energy bond for loading myosin head
ADP + P
28
myosin head pivoting
power stroke
29
myosin head lets go of actin
cross-bridge detachment
30
Duration of neural stimulus, Number of free calcium ions in sarcoplasm, Availability of ATP all affects
contraction duration
31
Ca2+ concentrations fall, Ca2+ detaches from troponin, active sites are re-covered by tropomyosin.
relaxation phase of skeletal muscle
32
_______ does not return muscle to original Length, _______ muscle must contract.
relaxation, opposite
33
A fixed muscular contraction after death. SR breaks down, calcium floods muscle cell, no ATP to bind to myosin and detach cross bridge.
rigor mortis
34
__ releases ____ when a motor neuron stimulates the muscle fiber
SR, Ca2+
35
Free ____ in the sarcoplasm triggers ___________
Ca2+, contraction
36
Contraction is an _____ process requiring ___
active, ATP
37
Relaxation and return to resting length are ______
passive