ch10pt3 Flashcards

(50 cards)

1
Q

length of sarcomere is related to how much zone of overlap there is. how much over lap is related to how many ___ ___ can grab on to ___

A

myosin heads, actin

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2
Q

The number of pivoting cross-bridges, the fiber’s resting length at the time of stimulation, and the frequency of stimulation all affect ____ ____

A

tension production

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3
Q

_____ __ _____ between thick and thin fibers and number of pivoting cross bridges affects Length-Tension Relationships

A

amount of overlap

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4
Q

______ ______ produces greatest amount of tension

A

optimum overlap

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5
Q

Too much or too little overlap reduces efficiency because

A

no room for sarcomere to contract, myosin heads can’t reach active sites on actin (too far away)

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6
Q

optimal rest length of sarcomere

A

2-2.5 micrometers

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7
Q

no tension will be produced if sarcomere is <___ or >____ of optimal length

A

60%, 175%

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8
Q

skeletal system limits __________ of muscles

A

overstretching

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9
Q

CNS monitors resting sarcomeres and maintains muscle ____

A

tone

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10
Q

must be reached for action potential to be generated in muscle fiber

A

threshold voltage

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11
Q

at threshold voltage, a single neural stimulus causes a

A

twitch

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12
Q

sustained muscle contractions require

A

repeated stimuli

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13
Q

phases of a twitch (3)

A

latent period, contraction phase, relaxation phase

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14
Q

Muscle has been stimulated, Not yet contracting

A

latent period

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15
Q

The action potential moves through t-tubules, Ca2+ released from SR

A

latent period

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16
Q

Elastic components tensed (_______ Tension)

A

latent period, Internal

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17
Q

Phase which sarcomere shortens, Tension builds to peak (_____ Tension)

A

contraction phase, External

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18
Q

Ca2+ levels fall, Active sites are covered and tension falls to resting levels

A

relaxation phase

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19
Q

The normal range of sarcomere lengths in the body is ___ to ___ percent of the optimal length.

A

75, 130

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20
Q

successive stimulations before the end of relaxation phase. Increases tension in a wave patterns

A

wave summation / temporal summation

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21
Q

Rapid stimulation continues, twitches reach maximum tension, muscle is in sustained fluttering contraction

A

incomplete tetanus

22
Q

If stimulation frequency is high enough, muscle never begins to relax, and is in continuous contraction (Not a normal physiologic state)

A

complete tetanus

23
Q

Bacteria Clostridium tetani releases a toxin. CNS cannot inhibit unwanted contractions.

24
Q

Results in Spastic Paralysis
“LockJaw”

25
Bacteria Clostridium botulinum releases a toxin. _______ toxin blocks Ach release. Results in flaccid paralysis.
botulism
26
types of contraction (2)
isotonic and isometric
27
Skeletal muscle changes length resulting in motion
isotonic contraction
28
if muscle tension is greater than load (resistance), muscle will ______, causing _______ contraction (flexion)
shorten, concentric
29
if muscle tension is less than load (resistance), muscle will ______, causing _______ contraction (extension)
lengthen, eccentric
30
Skeletal muscle develops tension equaling the load / resistance. Muscle does not change length.
isometric contraction
31
Used to maintain position / posture
isometric contraction
32
The pull of elastic elements (tendons, elastic components of sarcomere), expands the sarcomeres to resting/relaxed length.
elastic forces
33
to move body to original position, ______ ______ contract
opposing muscles
34
skeletal muscles exist in _______ pairs. one contracts, other lengthens, visa versa
opposing
35
Can take the place of opposing muscle contraction to return a muscle to its resting state
gravity
36
Provides Energy For Muscle Contraction. Sustained muscle contraction uses a lot of this energy. Myosin heads need this to be loaded into their cocked position.
ATP
37
myosin heads hydrolyze ATP to
ADP + Phosphate
38
Muscles store enough energy to start contraction. Muscle fibers must manufacture more ATP for
future contractions
39
active energy molecule used by muscles
adenosine triphosphate (ATP)
40
storage molecule for excess energy in resting muscle
creatine phosphate (CP)
41
using this enzyme ADP is recycled back into ATP by taking a phosphate from creatine phosphate (CP)
creatine kinase (CK)
42
this enzyme makes an ATP by taking a phosphate from ADP
myokinase
43
new ATP can be generated by
Aerobic metabolism or anaerobic glycolysis
44
Is the primary energy source of resting muscles and moderately active muscles. Breaks down fatty acids or pyruvic acid.
aerobic metabolism
45
Is the primary energy source for peak muscular activity. Produces two ATP molecules per molecule of glucose. Breaks down glucose stored in skeletal muscles (glycogen). Produces Lactic Acid.
anaerobic glycolysis
46
When muscles can no longer perform a required activity, they are
fatigued
47
Depletion of metabolic reserves, low pH (lactic acid buildup), muscle exhaustion and pain.
results of Muscle Fatigue
48
in the ____ _____, the removal and recycling of lactic acid is done by the _____
Cori Cycle, liver
49
Liver converts lactate to ______, then pyruvate to _____ (gluconeogenesis)
pyruvate, glucose
50
______ is released to recharge muscle glycogen reserves.
glucose