Ch.4 - Histology Flashcards
(126 cards)
What are the four primary tissue types
Epithelial tissues
connective tissue’s
muscle tissues
nervous tissues
Histology
Study of normal structures of tissues
epithelial tissues
Tightly packed sheets of cells with no visible ECM; cover and line all body surfaces and cavities; specialized form glands that manufacture secretion such a sweat saliva or chemical messengers called hormones
Connective tissue’s
Connect all other tissues and body to one another; ECM is a prominent feature for most connective tissue types with cells scattered throughout; bind, support, protect, and allow for transportation of substances
Muscle tissues
Capable of generating forced by contracting; little ECM between cells
Nervous tissue’s
Consisting of cells capable of generating, sending, receiving messages, and sells the support this activity all within a unique ECM
Extracellular matrix
Composed of substances in a liquid, Joe, or solid that around cells of a tissue
What are the two main components of the extracellular matrix
Ground substance and protein fibers
What are the functions of the ECM (extracellular matrix)
Provides tissue with strength to resist tensile (stretching) and compressive forces,
direct sales to their proper positions within a tissue and hold cells in place,
regulates development, mitotic activity, and survival of cells anything if you
Ground substance
Makes up most of ECM and consist of extracellular fluid; components include water nutrients ions and three families of micro molecules
what are the three families of macromolecules found in ground substance
Glycosaminoglycan’s,
proteoglycans,
cell adhesion molecules
Proteoglycans
Bound to a protein core helps make ECM firm or more solid and resistant to compression by “aggregation”
Cell adhesion molecules
Made up of different types of glycoproteins
adheres surroundings; holds everything in place within the ECM,
maintains normal tissue agriculture
Protein fibers
Embedded within ground substance; long molecules composed of multiple fibrous subunits with a rope like structure; enormous tensile strength
What are the three protein fibers found within the ECM
Collagen fibers, elastic fibers, reticular fibers
Collagen fibers
Make up 20–25% of all proteins in the body; composed of multiple repeating subunits that form a white fibrous proteins; resistant to tension (pulling a stretching forces) and pressure
Elastic fibers
Composed of protein elastin surrounded by glycoproteins; extensibility allows fiber to stretch up to 1 1/2 times resting length without breaking; once stretched, fibers return to resting length
Reticular fibers
Thin, short collagen fibers; form a meshwork of scaffold the support cells and ground substance of many tissues; form a weblike structure in organs like the spleen that help trap foreign cells
What are some diseases of collagen and elastic fibers (two)
Ehlers- Danlos syndrome,
Marfan syndrome
Ehlers Danlos syndrome
Abnormal collagen fibers; re-current joint dislocation, hyperextensibility of skin, fragility of blood vessels, easy bruising, plus various effects and intestines, heart, and lungs
Marfan syndrome
Abnormal elastic fibers; tall stature with long limbs and fingers; multiple skeletal abnormalities, recurrent joint dislocations, heart valve and lens (eye) abnormalities and dilation of aorta; aortic dissection(rupture) is most lethal complication
Cell junctions
Ways that cells bind to one another
What are the three major types of cell junctions
Tight junctions,
desmosomes,
gap junctions
Tight junctions
Hold cells closely together such that the space between is impermeable to movement of macromolecules