CH4 VOLATILE ANESTHETICS

Question 1

Highest MAC for neonates 3.3%
6-12 months infants 3.2%
6-12 months infants 2.5

Answer 1

SEVOFLURANE

Question 2

HIGHEST MAC during infants 1-6 months

Answer 2

ALL VOLATILE GAS EXCEPT Sevoflurane

Question 3

VOLATILE anesthetics
_____ Tv
_____ rr

Answer 3

DECREASE TV

INCREASE RR

Question 4

less waste to into the OR
hypoxic mixture
rebreathing of expired gas
more rapid depletion of c02 absorbent

Answer 4

LOW FLOW ANETHESIA

Question 5

c02
methane
n20

Answer 5

green house gases

Question 6

low blood/gass coef (0.42)
airway irritant ( coughing, breath holding / laryngospasm)
pungent

inc conc > inc heart rate and bp

Answer 6

DESFLURANE

Question 7

blood/gas partition coefficient :

sevoflurane

Answer 7

0.65

Question 8

blood/gas partition coefficient :

N2O

Answer 8

0.46

Question 9

blood/gas partition coefficient :

desflurane

Answer 9

0.42

Question 10

blood/gas partition coefficient :

isoflurane

Answer 10

1.5

Question 11

blood/gas partition coefficient :

enflurane

Answer 11

1.9

Question 12

blood/gas partition coefficient :

halothane

Answer 12

2.5

Question 13

SAME VAPOR PRESSURE ?

can interchange

Answer 13

HI
halo 243
iso 238

SEEN
SEVO 160
enflurane 172

des 665

Question 14

Filling a vaporizer with an agent whose vapor pressure is higher result to a _____ concentration

Answer 14

HIGHER

Question 15

Filling a vaporizer with an agent whose vapor pressure is lower result to a _____ concentration

Answer 15

LOWER

Question 16

does not alter arterial blood pressure , SV ,SVR, baroreceotor reflex

increases HR
mild inc CO

dose dependent direct myocardial depressant due to symphathetic activation

Answer 16

N2O

Question 17

causes DEC IN SVR

Answer 17

DIS

DESFLURANE
ISOFLURANE
SEVOFLURANE

Question 18

causes direct myocardial contractility

Answer 18

HE

HALOTHANE
ENFLURANE

Question 19

Dec CO

Answer 19

HALOTHANE

Question 20

MAINTAIN CO

Answer 20

DIS
DESFLURANE
ISOFLURANE
SEVOFLURANE

Question 21

INC CO

Answer 21

N20

Question 22

ANTIGEN INDUCED bronchospasm
not reduce cardiac ouput
dec SV, MAP, SVR
inc HR ( baroreceptor)

Answer 22

ISOFLURANE

Question 23

inc blood pressure and HR( inc conc rapidly)
airway irritation
sympathetic response

Answer 23

DESFLURANE

Question 24

lowest solubility constant

Answer 24

DESFLURANE

0.42

Question 25

highest blood gas solubility

Answer 25

HALOTHAN 2.5 | ISOFLURANE 1.5

Question 26

low gas/blood solubility | gases more in the _____

Answer 26

ALVEOLI

Question 27

high gas/blood solubility | gases more in the _____

Answer 27

BLOOD

Question 28

rate of uptake is influenced by ?

Answer 28

CO blood /gas solubility coefficient alveolar to venous partial pressure difference

Question 29

lower CO

Answer 29

inc FA/F1

Question 30

vessel rich group?

Answer 30

``` 75% CO 10 % TBW BRAIN HEART SPLEEN LIVER SPLENIC BED KIDNEYS ENDOCRINE GLAND ```

Question 31

high vapor pressure 654mmHg

Answer 31

DESFLURANE

Question 32

a gradient of _____mmhg between PaC02 and EtCO2

Answer 32

2-5mmHg

Question 33

ETcO2 decrease by:

Answer 33

``` in MV HYPOTHERMIA PULMO EMBOLISM SEVERE HYPOTENSION LOW CO CARDIAC ARREST ```

Question 34

ETcO2 increase by:

Answer 34

``` HYPOVENTILATION REBREATHING OF EXHALED GASES INCREASED ABSORPTION CO2 ( lap) MH SEPSIS ```

Question 35

DOES NOT REDUCE CO | OR CARDIAC INDEX

Answer 35

DIS DESLFURANE ISOFLURANE SEVOFLURANR

Question 36

For poorly soluble anesthetics such as n2O , transpulmonary shunting only slightly _______ rate of rise in the Fa/Fi

Answer 36

accelerates

Question 37

Gases with presrvatives?

Answer 37

HALOTHANE - thymol | methoxyflurane

Question 38

VRG reached steady state ina bout?

Answer 38

12 minutes

Question 39

which gas is soluble to plastic?

Answer 39

METHOXYFULRANE ISOFLURANE and Halothane soluble plastic and rubber lesser extent DIN- no solubke

Question 40

Inc concentration of COMPOUND A

Answer 40

``` Fresf absorbent sola lime or baralyne high absorb temp high con of sevo closed circuit low flow anesthesia ```

Question 41

Calcium hydroxide ambsorb does produce compound A?

Answer 41

NOOO it dows not have naOH and KOH

Question 42

percent of recovered metabolite

Answer 42

sevo 2-5% iso 0.2% des 0.02 % methoxy 50 %

Question 43

Wash un filling circuit ? litter?

Answer 43

7L bag 3l hise 2l absorbent 2"

Question 44

which gas? Heart rate 1l- dec SVR- no change Cardiac Index- dec

Answer 44

HALOTHANE

Question 45

which gas? Heart rate - dec SVR- dec Cardiac Index- dec all dec

Answer 45

SEVOFLURANE

Question 46

which gas? Heart rate - inc SVR- dec Cardiac Index- no change slig unc

Answer 46

ISOFLURANE

Question 47

which gas? Heart rate 1m- inc SVR- dec Cardiac Index- dec

Answer 47

DESFLURANE

Question 48

ISOFLURANE

Answer 48

dec svr inc hr maintain co

Question 49

context 1/2 gases 1hr

Answer 49

1hr anesthestic 95 reduction des 5 minutes ( 0.45) sevo 18 minutes (0.65) iso 30 minutes (1.64)

Question 50

how to compute for brain time constant

Answer 50

brain/ blood part coefficient x2

Question 51

time constant of volatile ?

Answer 51

1 min - 63 % 2min - 84% 3 min - 95% 3xtime constant=95 %

Question 52

What the effect of the following on your FI? inc FGF dec VC

Answer 52

INCREASED Fi colllapse bag

Question 53

What the effect of the following on your FI? inc FGF dec VC

Answer 53

inc FI