CH.5

Question 1

if a cell were to make copies of itself what is that called

Answer 1

proliferation

Question 2

what 2 cells does a multipotent SC differentiate into

Answer 2

myeloid and lymphoid

Question 3

what is the 1st stage of a normoblast

Answer 3

multipotent SC

Question 4

what is the 2nd stage of a normoblast

Answer 4

pronormoblast

Question 5

what is the 3rd stage of a normoblast

Answer 5

basophilic normoblast

Question 6

what is the 4th stage of a normoblast

Answer 6

polychromatophilic normoblast

Question 7

what is the 5th stage of a normoblast

Answer 7

orthochromic normoblast

Question 8

what is the 6th stage of a normoblast

Answer 8

shift reticulocyte

Question 9

what is the 7th stage of a normoblast

Answer 9

reticulocyte

Question 10

what is the 8th stage of a normoblast

Answer 10

erythrocyte

Question 11

if a multipotent SC becomes a pronormoblast what does that tell you about that cell’s fate

Answer 11

it will become a RBC

Question 12

can a basophilic normoblast go back to the pronormoblast stage

Answer 12

no

Question 13

what is the last stage of proliferation for a normoblast

Answer 13

polychromatophilic normoblast

Question 14

T or F: younger cells will be larger

Answer 14

T

Question 15

T or F: the nucleus will be smaller in younger cells

Answer 15

F

Question 16

T or F: chromatin pattern is diffused in young cells

Answer 16

T

Question 17

T or F: younger cells will have nucleoli

Answer 17

T

Question 18

T or F: reticulocytes are not basophilic

Answer 18

F

Question 19

is RNA basic or acidic

Answer 19

acidic

Question 20

what are the 2 erythroid progenitors

Answer 20

burst-forming unit-erythroid (BFU-E) and Colony-forming unit-erythroid (CFU-E)

Question 21

what is the 1st stage of a erythroid that you can see in a microscope

Answer 21

pronormoblast

Question 22

T or F: orthochromic normoblast have a nucleus

Answer 22

T

Question 23

how long does it take for reticulocyte to brake down all nucleonic RNA

Answer 23

48 hrs

Question 24

how long does it take for a SC to become a RBC

Answer 24

21 Days

Question 25

what is the American name for an immature RBC

Answer 25

normoblastic

Question 26

what is the british name for an immature RBC

Answer 26

erythroblast

Question 27

what is the european name for an immature RBC

Answer 27

rubriblast

Question 28

T or F: if a RBC needs to make more hemoglobin after it is mature it can

Answer 28

F

Question 29

when does a RBC stop producing hemoglobin and enzymes

Answer 29

after they lose their nucleus

Question 30

what does not stain in a pronormoblast

Answer 30

Golgi body and RNA

Question 31

what do they call the areas that do not stain in a pronormoblast

Answer 31

hof

Question 32

what kind of chromatin do basophilic normoblast have

Answer 32

cobble stone pattern

Question 33

what color is the cytoplasm of a polychromic normoblast

Answer 33

pinkish

Question 34

what is the function of the nucleus in the orthochromic normoblast stage

Answer 34

nothing, it is shut down

Question 35

what is the blueish color of reticulocytes on a wright stain called

Answer 35

polychromasia

Question 36

just using wright stain is sufficient enough to confirm reticulocytes? if not how do you confirm?

Answer 36

no; they also need to be stained with methylene blue

Question 37

what does methylene blue stain in reticulocytes

Answer 37

RNA

Question 38

what controls the production of RBCs

Answer 38

erythrokinetics

Question 39

what is a stimulent of erythropoiesis

Answer 39

hypoxia

Question 40

def? a state in which oxygen is not available in sufficient amounts at the tissue level to maintain adequate homeostasis

Answer 40

hypoxia

Question 41

what organ releases erythropoietin

Answer 41

kidneys

Question 42

T or F: erythropoietin inhibits apoptosis

Answer 42

T

Question 43

what would be the level of erythropoietin in females at the end of their period

Answer 43

high

Question 44

how long does a RBC live

Answer 44

120 days

Question 45

what happens to the 10-15% of erthroid precursors that never mature

Answer 45

they are destroyed

Question 46

is extra or intra vascular hemolysis more common

Answer 46

extravascular

Question 47

what kind of erythrocyte destruction happens in the organs such as the spleen or liver

Answer 47

extravascular

Question 48

what kind of erthrocyte destruction happens within the blood vessel

Answer 48

introcascular hemolysis

Question 49

what is cellularity

Answer 49

ratio of myloid cells to fat cells in bone marrow

Question 50

what does it mean if someone has 20% cellularity

Answer 50

20 myeloid cells to 80 fat cells