CH.6 Flashcards

1
Q

how many ATPs does glycolysis make

A

4

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2
Q

what is the net ATP for RBCs during glycolysis

A

2

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3
Q

what is the most important energy source in glycolysis

A

glucose

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4
Q

what is the purpose of glycolsis

A

break down glucose

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5
Q

what do free radical do

A

take away e-

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6
Q

what reduces glutathione

A

NADPH

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7
Q

what converts H2O2 to 2 H20

A

glutathione

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8
Q

funtion of BPGM

A

changes the position of the phosphate

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9
Q

if glycolisis takes the BPGM pathway what happens to ATP production

A

skips making 1 ATP

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10
Q

what does 2,3-bisphosphoglycerate bind to

A

hemoglobin

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11
Q

if O2 can not bind to hemoglobin because of 2,3-bisphosphoglycerate what happens

A

O2 is released in the tissues

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12
Q

what gets detoxified in the hexose monophosphate pathway

A

peroxide

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13
Q

what changes glucose-6-phosphate to pentose phosphate in the hexose monophasphate pathway

A

glucose-6-phosphate dehydrogenase (G6PD)

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14
Q

what is the most common enzyme deficiency

A

G6PD

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15
Q

what do degmacytes indicate

A

heinz bodies

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16
Q

what do macrophages do to RBCs with ozidized hemoglobin when they pass through the spleen

A

they destroy part of it

17
Q

how many iron molecules are in a RBC

18
Q

is ferrous hemoglobin reduced or oxidized

19
Q

is ferric hemoglobin reduced or oxidized

20
Q

can O2 bind to methemoglobin

21
Q

what condition does glutamate replace valine in position 67 on the beta chain

A

hemoglobin M

22
Q

does methemoglobin increase or decrease in Hemoglobin condition

23
Q

what medicine do people take with hemoglobin M condition

A

metholine blue pill

24
Q

T or F: methylene blue is a reducing agent

25
what changes when a RBC becomes a target cell
change in the phospholipid bilayer
26
what is the reason why when 2 RBC touch they don't merge
glycolipids
27
what kind of proteins connect horizontal proteins to mmb
vertical
28
what happens to a RBC if it's shape is changed
it will die
29
what happens to a RBC deformability as they age
it decreases
30
if there is a problem with a RBC horizontal proteins what kind of cell will it be
elipocyte
31
what kind of environment would you find spherocytes
hypotonic
32
what kind of environment would you find enchinocytes
hypertonic
33
what kind of environment would you find normal RBC
isotonic