Chap 10 Quiz Flashcards

(32 cards)

1
Q

The two locations of triacylglycerol digestion

A

Mouth and Stomach

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2
Q

The lipase for mouth and stomach

A

Mouth - lingual lipase

Stomach - gastric lipase

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3
Q

Both lipases for triacylglycerol digestion are active at

A

low pH

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4
Q

Triacylglycerol Digestion does not require

A

other proteins cofactors for max. activity

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5
Q

Synthesis of Triacylglycerols occurs predominantly in

A

enterocytes

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6
Q

Lipoproteins defined

A

Spherical micelles of phospholipids and apolipoproteins surrounding a neutral lipid core

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7
Q

Examples of Lipoproteins

A

HDL
IDL
LDL
VLDL

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8
Q

Structure of a Lipoprotein

A

Triglyceride and cholesteryl ester core

Phospholipid and cholesterol coat

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9
Q

Three mechanisms in which lipids enter the cell

A

Diffusion

Transport

Receptor-mediated endocytosis

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10
Q

Receptor-mediated endocytosis defined

A

Process in which the cell internalizes particles and uses the cholesterol contents of low-density lipoproteins

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11
Q

What binds to the receptor in receptor-mediated endocytosis

A

Ligand (clathrin)

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12
Q

Triacylglycerol Synthesis occurs where

A

liver and adipose tissue

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13
Q

Triacylglycerol Synthesis in the liver

A

de novo synthesis from actyl-CoA

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14
Q

Triacylglycerol Synthesis in adipose tissue

A

Re-esterifies free fatty acids (storage)

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15
Q

Enzymes for triacylglycerol synthesis are found in

A

the endoplasmic reticulum

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16
Q

In digestion lipids are emulsified by

A

bile salts into smaller droplets

17
Q

Pancreatic lipase hydrolyzes

A

ester bonds in triacylglycerols releasing fatty acids

18
Q

Triacylglycerols are packaged into what form to travel the blood stream

19
Q

Lipoprotein are complex particles composed of

A

Lipids (cholesterol/triglycerides) & Proteins

20
Q

Chylomicrons are the

A

largest and least dense lipoproteins and are primarily transporting dietary triglycerides from intestine to tissue

21
Q

HDL are synthesized in the ____ and involved in _____

A

liver; reverse cholesterol transport for excretion

22
Q

Diffusion is a _____ process for lipoproteins

A

passive; moves from areas of high concen. to lower

23
Q

Transport involves specific

A

carrier proteins embedded in cell membranes

24
Q

Receptor-Mediated Endocytosis specific process involving

A

the binding of extracellular ligands

25
Reverse Cholesterol transport defined
Removal of cholesterol from the circulation and peripheral tissue to the liver
26
Enzyme that catalyzes the dephosphorylation of phosphatidate to diacylglycerol
Lipin
27
Lipid Storage droplets defined
The organelle that stores neutral lipids in the cells
28
Lipolysis Defined
The regulated mobilization and breakdown of triacylglycerols
29
**Lipolysis defined (extra)
triggered by hormone signaling Occurs at low background levels Regulated by AMP kinase
30
Types of triacylglycerol storage
Acute and chronic
31
Acute storage
+ Mobilization occurs over minutes to hours +cAMP is manipulated via hormones and cell signaling cascades
32
Chronic storage
+ Occurs over weeks or longer + Partially affected by both levels of gene expression and diet