Chapter 1 of Clayden

Question 1

Name an Alkaloid famous in the 16th Century

Answer 1

Quinine, or “Jesuit’s Bark”, used to treat fevers, especially malaria

Question 2

Name two compounds from coal in the 19th Century that were applied

Answer 2

Phenol was used as an antiseptic

Aniline was used as a dye-stuff

Question 3

Name the compounds found in brown tar distilled from coal

Answer 3

Benzene
Phenol
Aniline
Pyridine 
Thiophene

Question 4

What is Volatile liquid

Answer 4

Liquid that evaporates at room temperature

Question 5

What happened in Freiburg, Germany in 1889?

Answer 5

Attempts to make thioacetone by the cracking of trithioacetone gave rise to ‘an offensive smell which
spread rapidly over a great area of the town causing fainting, vomiting and a panic evacuation. the
laboratory work was abandoned’.