Chapter 10 Flashcards
Diseases and immunity (12 cards)
Describe a pathogen
a disease-causing organism
Describe a transmissible disease
a disease in which the pathogen can be passed from one host to another
Describe transmission of pathogens
direct contact: through blood and other body fluids
indirect: contaminated surfaces, food, animals and air
Describe the body defenses
skin, hairs in the nose, mucus, stomach acid and white
blood cells
Describe active immunity
defence against a pathogen by antibody production in the body
Describe antibodies
proteins produced by lymphocytes that bind to antigens leading to direct destruction of pathogens or marking of pathogens for destruction by phagocytes, there shape needs to be complimentary to the shape of the antigens for them to bind
Explain active immunity
Some of the lymphocytes that produced the specific antibodies, as a result of infection by a pathogen, remain in the lymph nodes as memory cells for some time, and can divide rapidly to produce more antibodies to respond to further infections by the same pathogen. This creates immunity to the disease caused by the antigen.
Describe how active immunity can be gained via vaccination
Vaccination: weakened form of the pathogen that has antigens, or antigens from the pathogen
The presence of the antigens triggers an immune response:
lymphocytes make specific antibodies to combat possible infection some remain in the lymph nodes as memory cells that can reproduce quickly and produce antibodies in response to any subsequent invasion of the body by the same pathogen providing long-term immunity.
Explain the role of vaccination in controlling the
spread of diseases
reduces transmission – herd immunity, which helps prevent disease outbreaks
Explain passive immunity
short-term (no formation of memory cells) defence against a pathogen by antibodies acquired from another individual, including across the placenta and in breast milk (antibodies provide the baby with protection against infection at a time when the baby’s immune responses are not yet fully developed)
Describe and explain cholera
a disease caused by a bacterium which is transmitted in contaminated water : cholera bacterium produces a
toxin that causes secretion of chloride ions into the s.i. causing osmotic movement of water into the gut, causing diarrhoea, dehydration & loss of ions from the blood
check 10.1.5