Chapter 11: Nucleotide Biosynthesis Flashcards

1
Q

are polymers that consist of nucleotide residues

A

nucleic acid

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2
Q

located in the nuclei of the cell

A

nucleic acid

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3
Q

hereditary determinants of living organisms

A

nucleic acid

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4
Q

What is the elemental composition of nucleic acid?

A

carbon, hydrogen, oxygen, nitrogen, and phosphorus

or CHONPS

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5
Q

types of nucleic acid

A

DNA and RNA

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6
Q

what does DNA mean?

A

deoxyribonucleic acid

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7
Q

what does RNA mean?

A

Ribonucleic acid

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8
Q

what is the structure of nucleic acids?

A

polynucleotides

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9
Q

what are the building blocks of the nucleic acid structure?

A

nucleotides

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10
Q

describe the nucleotide structure

A

phosphate

then

sugar (ribose or deoxyribose)

then

base (purines and pyrimidines)

then pointing towards

nucleotide

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11
Q

a sugar that is naturally produced by the body from food

A

ribose

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12
Q

a sugar derived from ribose by replacing a hydroxyl group with hydrogen.

A

deoxyribose

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13
Q

dna is made of ___

A

2 strands of polynucleotide

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14
Q

the sister strands of the DNA run ___

A

in opposite directions (antiparallel)

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15
Q

sister strands are joined ___

A

by the bases

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16
Q

Each base is paired with a specific partner:

A is always paired with ___

A

T

17
Q

Each base is paired with a specific partner:

G is always paired with ___

A

C

18
Q

Each base is paired with a specific partner:

Purine is always paired with ___

A

Pyrimidine

19
Q

Thus the sister strands are ___ but ___

A

complimentary

identical

20
Q

the bases of sister strands are joined by ___

A

hydrogen

21
Q

The structure of DNA can be understood in terms of 3 levels of structure:

A

Primary
Secondary
Tertiary

22
Q

refers to the sequence of its nucleotide residue

A

primary structure

23
Q

it pertains to the helix formed by two DNA strands

A

secondary structure

24
Q

refers to the 3 dimensional shape. Arises from supercoiling where double helix is being twisted into compact shape

A

tertiary structure

25
Q

two chemical compounds that cells use to make the building blocks of DNA and RNA.

A

Purine

Pyrimidine

26
Q

Examples of Purine

A

adenine and guanine

27
Q

Examples of Pyrimidine

A

cytosine, thymine, and uracil

28
Q

are used to make DNA

A

Cytosine and thymine

29
Q

are used to make RNA

A

cytosine and uracil

30
Q

a. The parent molecule has 2 complementary strands of DNA. Each base is paired by ___ with its specific partner

A

hydrogen bonding

31
Q

b. The first step in replication is ___

A

the separation of the two DNA strands

32
Q

c. Each parental strand now serves as ___ that determines ___

A

template

the order of nucleotides along a new complementary strand

33
Q

d. The nucleotides are connected to form the ___ of the new strands

Each “daughter” DNA molecule consists of ___

A

sugar-phosphate backbones

one parental strand and one new strand

34
Q

any permanent change in the primary structure of the (sequence of nucleotides residues in) DNA is called ___

A

mutation

35
Q

Mutations might involve ___

A

the switching of one base pair for another

or

addition of deletion of base pairs

36
Q

mutation causing agents

A

mutagens

37
Q

examples of mutagens

A

x rays
UV radiation
nuclear radiation
chemicals

38
Q

errors in replication and exposure to mutagens common causes of muations

A

errors in replication and exposure to mutagens include

39
Q

what is it called when the mutations are in the sex cells and inherited

A

genetic diseases