chapter 12 Flashcards
(22 cards)
what are the three types of muscle
-skeletal muscle: striated, somatic NS
-cardiac muscle: striated, ANS
-smooth muscle: no striations, ANS; constricts hollow organs
skeletal muscle brief description
-skeletal and cardiac muscle are made in a similar way, account for striations due to development.
-work in antagonistic pairs: contract and relax around joints
-only excitable
-contract in a linear patter: one flexes (shortens), while the other relaxes (lengthens)
muscle cell terminology
muscle fiber
modified ER terminology
sarcoplasmic reticulum
cytoplasm
sarcoplasm
cell membrane
sarcolemma
skeletal muscles are important for
interacting with environment
how much weight does striated muscle account for in the adult body
40-50 percent
how much do muscles consume at rest
25 percent of oxygen
skeletal muscle
group of fascicles, muscle fiber cells are multinucleated
fascicle
bundle of muscle fibers, made of myofibril
- endomyosin
CT around a muscle fiber
- perimysium
CT around a fascicle
- epimysium
CT around a bundle of fascicles= makes muscle, also has blood supply and nerves
t tubules
transverse tubules
-created when the sarcolemma invaginates
lateral sacs
terminal cristae
-swelling of sarcoplasmic reticulum in close proximity to t-tubule. stores calcium
sarcomere
contractile unit of skeletal muscle, made z line to z line
-proteins: thick and thin filaments are found within and partially overlap each other
myofribril
grouping of proteins, sarcomeres lined together, forms a small part of entire muscle cell.
ultrastructure of muscle
molecular anatomy of a muscle cell, close examination of a sarcomere. has two contractile proteins: actin and myosin that represent thick and thin filaments
contractile proteins
myosin
part of thick filament
-approx 250 join to form a thick filament
-quarternary structure: has 4 subunits; 2 heavy chains= tail, 2 light chains= head
-every head has a site for actin binding and another active site for ATPase
contractile proteins
actin
makes thin filaments
-double helix of g-protein (globular) molecules
-each g-actin has a binding site for myosin
-strands of g-actin= called f-actin (fibrous)
what are the regulatory proteins found on the thin filaments?
- tropomysosin: regulatory protein that covers the binding site on f-actin
- troponin: regulatory protein bound to tropomyosin and has a binding site for calcium.