Chapter 12: Endocrine System Flashcards

(50 cards)

1
Q

What system consists of ductless glands whose parenchymal cells synthesize and secrete their products - the hormones, directly into the blood and lymph capillaries?

A

endocrine system

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2
Q

The endocrine system consists of ductless glands whose parenchymal cells synthesize and secrete their products which are ?, directly into the blood and lymph capillaries

A

hormones

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3
Q

What gland is suspended by a stalk from the hypothalamus at the base of the diencephalon. It rests in a saddle-like depression in the sphenoid bone, the sella turcica, behind the optic chiasm.

A

pituitary gland

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4
Q

What arises as an upward evagination of the ectoderm lining the primitive oral cavity. It contacts and fuses with the neurohypophyseal downward.

A

adenohypophysis

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5
Q

What arises as downward growth of the neural ectoderm of the hypothalamus and is therefore actually a part of the brain?

A

neurohypophysis

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6
Q

The hypothalamic hormones that control the function of the adenohypophysis are the?

A

releasing factors or the inhibitory factors

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7
Q

From the hypothalamus, what are carried to the adenohypophysis? they then stimulate certain cells to secrete and release specific hormones into the circulation.

A

releasing factors

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8
Q

What is the largest subdivision of the pituitary. It is made up of clusters and cords of cells in close apposition to a dense network of sinusoidal capillaries.

A

Pars distalis (pars anterior)

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9
Q
  • This type of cell in the Pars Distalis is pale staining or have little affinity for stains that appear clear or white in tissue sections. It is believed to be partially degranulated acidophils or basophils.
  • Usually clustered and may form the center of a cord of cells.
  • Considered reserved cells that are capable of differentiating into chromophilic cells or they may be cells in the process of degranulation.
  • Generally, 50% of the cells in the pars distalis are these cells.
A

Chromophobes (Chromophobic cells, Chief cells, Principal cells, Reserve cells, C cells or Gamma cells)

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10
Q

What subpopulations of chromophobes have numerous fine processes interspersed between the other cells of the pars distalis. They may have phagocytic functions.

A

Stellate cells

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11
Q

What subpopulations of chromophobes contain sparse granules. They are undifferentiated neurosecretory cells, which may be stem cells.

A

Resting degranulated chromophils

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12
Q

What are the predominant chromophobe type which form from a stromal network that supports the chromophils.

A

Follicular cells

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13
Q

What are hormone-secreting cells of the adenohypophysis that stains intensely owing to their abundant cytoplasmic secretory granule?

A

Chromophils

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14
Q

What type of chromophilic cell secrete simple proteins with an acidophilic cytoplasm and stain intensely with eosin and orange G, but not with PAS. More abundant in the periphery of the gland, they are usually smaller than basophils and their eosinophilic granules are larger and numerous.

A

Acidophils

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15
Q

What type of hormone secreting cell of acidophils predominate in the lateral portions of the pars distalis have a distinct affinity for orange G. They are cells that secrete growth hormone (or GH, somatotropin).

A

Somatotropes

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16
Q

Somatotropes are cells that secrete ? It stimulate general body growth, uptake of amino acids, and protein synthesis. It also induces proliferation of cartilage cells in the epiphyseal plates of developing or growing long bones.

A

growth hormone (or GH, somatotropin)

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17
Q

What stain with erythrosin and carmeosin L, especially when the cells are hypertrophied and contain many granules, as in pregnancy and lactation, or when nonpregnant animals are treated with estrogen. They are cells that produce the lactogenic hormone prolactin, which stimulates development of the mammary gland during pregnancy.

A

Mammotropes (lactotropes or prolactin cells)

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18
Q

Mammotropes are cells that produce the lactogenic hormone called ?, which stimulates development of the mammary gland during pregnancy. After parturition (birth), it maintains milk production in the mammary glands during lactation.

A

prolactin

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19
Q

What type of chromophilic cell secrete glycoproteins with a basophilic cytoplasm; stain well with hematoxylin and other basic dyes; they are PAS positive. More abundant in the core of the gland, usually larger than acidophils, with fewer and smaller granules.

A

Basophils

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20
Q

What secrete the thyroid-stimulating hormone (or TSH, thyrotropin)?

A

Thyrotropes

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21
Q

What cells stimulates synthesis and secretion of the thyroid hormones thyroxin and triiodothyronine from the thyroid gland?

A

thyroid-stimulating hormone (or TSH, thyrotropin)

22
Q

What are cells that secrete Follicle Stimulating Hormone (FSH) and Luteinizing hormone (LH) or Interstitial Cell Stimulating Hormones (ICSH) in male.

23
Q

In females, what hormone promotes estrogen secretion and growth and maturation of the ovarian follicles?

A

Follicle Stimulating Hormone

24
Q

In males, what hormone stimulates spermatogenesis and secretion into the seminiferous tubules of the testes and androgen-binding protein of the Sertoli cells?

A

Follicle Stimulating Hormone

25
In females, what hormone functions in association with FSH to induce ovulation and to promote the final maturation of the ovarian follicles. LH is also responsible for the formation of corpus luteum in the ovary following ovulation and the secretion of the estrogen and progesterone from the cells of the corpus luteum.
Luteinizing hormone
26
In males, what hormone maintains and stimulates the interstitial cells (of Leydig) in the testes to produce the hormone testosterone?
Luteinizing hormone
27
Luteinizing hormone is sometimes called?
interstitial cell-stimulating hormone (ICSH)
28
What secrete adrenocorticotropic hormone (ACTH)?
Corticotropes
29
What influences the function of cells in the adrenal cortex. It also stimulates the synthesis and release of glucocorticoids from the zona fasciculata and zona reticularis of the adrenal cortex.
adrenocorticotropic hormone (ACTH) adrenocorticotropic hormone (ACTH)
30
What is a funnel-shaped superior extension of pars distalis, forms from a partial sleeve around the infundibulum of the neurohypophysis. Its histology is similar to pars distalis, but it contains mostly gonadodotropes. - Composed of cuboidal cells which are weakly basophilic. - Cells are disposed in cords or clusters or as follicles with small granules. - Contain many capillaries of the primary capillary plexus of the hypophyseal portal system.
Pars tuberalis
31
What is a narrow band or wedge of adenohypophyseal tissue between the pars distalis and pars nervosa that borders the neurohypophysis. - Rudimentary in man but well-developed in animals especially amphibians and fishes. - Secrete melanocyte-stimulating hormone (beta-MSH, intermedin).
Pars intermedia
32
What increases pigmentation of the skin by causing dispersion of the melanin granules?
melanocyte-stimulating hormone (beta-MSH, intermedin)
33
The axon of the hormone-synthesizing nerve cells of the hypophysiotropic area terminates in the external zone of the median eminence. They establish neurovascular contacts with the primary capillaries of the hypophyseal portal system to regulate hormone release by releasing or inhibiting hormones from the pars distalis
NEUROHYPOPHYSIS (POSTERIOR PITUITARY, PARS NERVOSA)
34
What subdivision of neurohypophysis consists of the infundibular stem (neural stalk) and the median eminence?
Infundibulum
35
What carries axons from the hypothalamus to the pars nervosa and contains the capillary loops of the primary capillary plexus?
stem
36
Part of the tuber cinereum forms the floor of the hypothalamus?
median eminence
37
What is the expanded lobe of the neurohypophysis that contains axon terminals and numerous capillaries?
Pars nervosa (infundibular process)
38
What contains many unmyelinated axons whose cell bodies are located mainly in the supraoptic and paraventricular nuclei of the hypothalamus?
neurohypophysis
39
Axons passing from these nuclei to the pars nervosa are together termed the?
hypothalamohypophyseal tract
40
The axons contain neurosecretory granules and exhibit large granule-filled dilation called?
Herring bodies
41
What is a 9-amino acid peptide synthesized mainly by the cells of the paraventricular nucleus. It stimulates milk ejection by the mammary glands and stimulates the contraction of the uterine smooth muscle during copulation and parturition.
Oxytocin
42
What is a 9-amino acid peptide synthesized mainly by cells in the supraoptic nucleus. It stimulates water resorption by the renal medullary collecting ducts and contraction of vascular smooth muscle.
Antidiuretic hormone (ADH, arginine vasopressin)
43
What is a binding protein that complexes with neuro-hypophyseal hormones?
Neurophysin
44
What acts as a source of chemical energy for the neurosecretory process?
ATP (adenosine triphosphate)
45
What surrounds the axon terminals in the pars nervosa pick up the neurosecretory products and convey them to the general circulation?
fenestrated capillary plexus
46
What are highly branched glial cells whose processes surround and support the unmyelinated axons?
Pituicytes
47
What gland is a small conical organ attaches by a stalk to the roof of the diencephalon near the posterior aspect of the third ventricle?
pineal gland
48
pineal gland contains clusters of globular, basophilic, calcified matrix known as ?, which increase in size and number and calcify with age.
brain sand (corpora arenacea)
49
These cells have large irregular nuclei with prominent nucleoli and pale basophilic cytoplasm. Secrete the indoleamine melatonin. Under continuous light stimulation, melatonin production decreases and gonadal activity increases.
Pinealocytes (Chief cells)
50
What are glial-like cells have elongated heterochromatic nuclei and long cytoplasmic processes that contain intermediate filaments. They are found around blood vessels and between clusters of pinealocytes.
Astroglial cells (Interstitial cells)