Chapter 12 Questions Flashcards

(9 cards)

1
Q

A newborn is diagnosed as having an incomplete separation between the aorta and the pulmonary artery (a mild form of persistent truncus arteriosus). Later, after. Corrective heart surgery, she has more colds and sore throats than her siblings. After testing, the physician tells the parents that there is evidence of immunodeficiency. The physician also tells the parents that it would be a good idea to check her levels of parathyroid hormone. What is the basis for this suggestion?

A

DiGeorge’s syndrome

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2
Q
Which of these cell and tissue types arises from cranial but not trunk, neural crest cells?
A. Sensory ganglia
B. Adrenal medulla
C. Melanocytes
D. Schwann cells
E. None of the above
A

E. None of the above

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3
Q
Which molecule is a poor substrate for migrating neural crest cells?
A. Laminin
B. Chondroitin sulfate 
C. Fibronectin
D. Type IV collagen 
E. Hyaluronic acid
A

B. Chondroitin sulfate

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4
Q
Neural crest cells arise from the:
A. Somite
B. Dorsal non-neural ectoderm
C. Neural tube
D. Splanchnic mesoderm
E. Yolk sac endoderm
A

C. Neural tube

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5
Q
A 6 month old infant exhibits multiple congenital defects, including a cleft palate, deafness, ocular hypertelorism, and a white forelock but otherwise dark on his head. The probable diagnosis is:
A. CHARGE association 
B. von Recklinghausen's disease
C. Hirschsprung's disease
D. Waardenburg's syndrome
E. None of the above
A

D. Waardenburg’s syndrome

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6
Q
What molecule is involved in the migration of neural crest cells from the neural tube?
A. Slug
B. BMP-2
C. Mash 1
D. Norepinephrine
E. Glial growth factor
A

A. Slug

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7
Q
Which is NOT a derivative of the neural crest?
A. Sensory neurons
B. Motor neurons
C. Schwann cells
D. Adrenal medulla
E. Dental papilla
A

B. Motor neurons

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8
Q
What maintains the competence of neural crest cells to differentiate into autonomic neurons?
A. Sonic hedgehog
B. Acetylcholine
C. Mash 1
D. Glial growth factor
E. Transforming growth factor-B
A

C. Mash 1

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9
Q
If trunk neural crest cells are transplanted into the cranial region, they can form all of the following types of cells except:
A. Pigment cells 
B. Schwann cells
C. Sensory neurons
D. Cartilage
E. Autonomic neurons
A

D. Cartilage

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