Chapter 8 Questions Flashcards
(8 cards)
1
Q
Phocomelia is most likely to be seen after maternal exposure to which teratogenic agent during the first trimester of the pregnancy? A. Alcohol B. Aminopterin C. Androgens D. Ionizing radiation E. Thalidomide
A
E. Thalidomide
2
Q
Which of these anomalies can be attributed to a disturbance in tissue resorption? A. Pelvic kidney B. Cleft lip C. Anal atresia D. Renal agenesis E. Amputated digit in utero`
A
C. Anal atresia
3
Q
Which of the following is responsible for the largest percentage of congenital malformations? A. Maternal infections B. Chemical teratogens C. Genetically based conditions D. Ionizing radiations E. Unknown factors
A
E. Unknown factors
4
Q
Folic acid deficiency is now believed to be a major cause of what class of malformations? A. Trisomies B. Neural tube defects C. Ambiguous genetalia D. Polyploidy E. Duplications
A
B. Neural tube defects
5
Q
Cleft palate is the result of a defect in what developmental mechanism? A. Failure to fuse B. Failure to merge C. Faulty inductive tissue interaction D. Disturbance in tissue resorption E. Absence of normal cell death
A
A. Failure to fuse
6
Q
An increased incidence of what condition is strongly associated with increasing maternal age? A. Trisomy 18 B. Trisomy 21 C. Trisomy 13 D. Anencephaly E. Ambiguous external genitalia
A
B. Trisomy 21
7
Q
What is likely the cause for a badly turned-in ankle in a newborn?
A
Insufficiency of amniotic fluid (oligohydramnios), which can place exposed parts of fetuses under excessive mechanical pressure from the uterine wall and lead to deformations of this type
8
Q
A 3 y.o. child is much smaller than normal, has sparse hair, and has irregular teeth. What is a likely basis for this condition of defects?
A
Dysplasia of ectodermal derivatives
