Chapter 14: Brain and Cranial Nerves Flashcards
Telencephalon.
Forms cerebrum and lateral ventricles.
Diencephalon.
Forms thalamus, hypothalamus, epithalamus and third ventricle. Superior to brainstem.
Mesencephalon.
Forms midbrain and cerebral aqueduct.
Metencephalon.
Forms pons, cerebellum and upper fourth ventricle.
Myencephalon.
Forms medulla oblongata and lower fourth ventricle.
Brainstem.
Continuous with spinal cord. Consists of medulla oblongata, pons and midbrain.
Where is the cerebellum?
Posterior to brainstem.
What is the largest part of the brain?
Cerebrum.
Describe the dura mater in the brain, and its layers.
Continuous with the dura mater in the spinal cord. Consists of an outer periosteal layer and an inner meningeal layer. These layers are fused together except for where they separate to enclose the dural Venus sinuses that drain venous blood from the brain.
What are the 3 extensions of the dura mater in the brain that separate parts of the brain?
Falx cerebri: separates the 2 sides of the cerebrum. Falx cerebelli: separates the 2 sides of the cerebellum. Tentorium cerebelli: separates the cerebrum from the cerebellum.
What is present in the spinal cord, but not in the brain?
Epidural space.
What are the main routes of blood flow to the brain?
Internal carotid artery and vertebral arteries.
What is the main route of blood flow from the brain?
The dural venous sinuses drain into the internal jugular veins.
How much oxygen and glucose does the brain consume?
20% of the body’s supply.
An interruption of blood flow for how many minutes distinguishes between impaired function vs. permanent damage?
Impaired neuronal function: 1-2 minutes. Permanent injury: 4 minutes.
Why must the supply of glucose to the brain be continuous?
No glucose is stored in the brain.
What are the components of the blood brain barrier?
Tight junctions between endothelial cells, and a thick basement membrane that surrounds the capillaries.
Which substances can diffuse across the BBB?
Lipid soluble, steroid hormones, alcohols, barbiturates, nicotine, caffeine, water molecules.
What causes breakdown of the BBB?
Trauma, toxins, inflammation.
Cerebrospinal fluid.
Clear and colourless liquid composed of mostly water. Protects the brain and spinal cord from chemical and physical injuries.
What are the components of CSF?
Water, oxygen, glucose, proteins, lactic acid, urea, cations, anions, WBCs.
How much CSF is in the body at all times, and how much is produced?
80-150 mL. Body produces 20 mL / hour.
What are the CSF-filled cavities in the brain?
Lateral ventricle 1, lateral ventricle 2, third ventricle and fourth ventricle.
What is the difference between lateral ventricles 1 and 2?
Each one is in its own hemisphere of the cerebrum.