Entire set of cellular metabolic reactions
Metabolic pathways can be divided into two types:
Anabolic and Catabolic
use ATP and reducing power to synthesize large biomolecules
produce ATP and combust carbon fuels to synthesize ATP
Amphibolic pathways can function...
Anabolically or catabolically (TCA can function as either depending on needs)
ATP consists of..
Adenine, ribose and triphosphate units (Tri-P contains the energy)
Hydrolysis of ATP is...
Exergonic (energy release)
The triphosphate unit of ATP contains two...
Phosphoanhydride bonds that are unstable
When phophoanhyride bonds are hydrolyzed,
They release a lot of energy for metabolic reactions and can assume a more stable state
Energy released by ATP hydrolysis powers...
What is phosphoryl-transfer potential?
Standard free energy of hydrolysis - means of comparing the tendency of organic molecules to transfer a phosphoryl group to an acceptor molecule
ATP has a high
Phosphoryl transfer potential to earn stability
ATP turnover is very ____ and the amount of ATP is very ______.
ATP must be ____________ to provide energy to power the cell.
Constantly recycled *Cells use and generate ATP at the same time, very busy*
How much ATP is needed for one day to survive?
Over 80lb of ATP
ATP is an activated carrier of phosphoryl groups. Other activated carriers are often derived from...
Activated carriers for electrons for fuel oxidation (used for ATP synthesis)
NADH (must be regenerated all the time) FADH2
Most activated carriers are limiting because they derive from vitamins. Why?
We cannot synthesize vitamins but they are essential in our diets
Activated carriers of electrons for reductive biosynthesis
NADPH (used for ATP)
The reactive part of NAD+ is the _____ and synthesized from _____.
Nicotinamide Ring and synthesized from the vitamin niacin
Nicotinamide Ring accepts ________ and ______ (NADH)
1 hydrogen ion and 2 electrons
The reactive part of FAD is the ________ - derived from _______.
Isoalloxazine Ring - derived from vitamin riboflavin
FAD accepts ______ and _______ (FADH2)
2 protons and 2 electrons
NADP+ is the ________ for reduction biosyntheses.
NADPH is used primarily for _________.
NADH is used for __________.
Generation of ATP