Chapter 17 - Respiratory System Flashcards

1
Q

Functions

A
  • Transfers O2 from air to blood
  • Transfers CO2 from blood to air
  • protective mechanisms to eliminate particles and pathogens
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2
Q

Conducting portions of the respiratory system

A
  • nasal cavity, nasopharynx, larynx, trachea, bronchi, bronchioles, terminal bronchioles
  • warms and humidifiers air
  • removes particles
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3
Q

Respiratory portions of the respiratory system

A
  • respiratory bronchioles, alveolar ducts, alveoli
  • sites of gas exchange
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4
Q

What is most of the conducting portion of the RS lined with?

A
  • respiratory epithelium
  • PSCCE
  • goblet cells - secrete mucus
  • brush cells - columnar cells w/ cilia, sensory receptors that trigger cough
  • basal cells - stem cells to replace ciliated cells, brush cells and goblet cells
  • small granule cells - release catecholamines and polypep hormones
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5
Q

What are the areas of the conducting portion of the RS above the larynx lined with? What sections are these?

A
  • stratified squamous epithelium
  • nasal vestibule, oropharynx, epiglottis, vocal folds
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6
Q

Trachea

A
  • lined with respiratory epithelium
  • 16-20 C-shaped hyaline cartilage rings that open posteriorly
  • mucus glands
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7
Q

Bronchi

A
  • branches of trachea
  • lined with respiratory epithelium
  • smooth muscle bunds in spiral arrangement
  • elastic fibers bc they have to expand
  • mucus glands
  • plates of cartilage, amount decreases with diameter
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8
Q

BALT

A
  • bronchus associated lymphatic tissue
  • nonencapsulated lymphatic tissue in bronchi
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9
Q

Bronchioles

A
  • terminal branches of bronchi
  • no cartilage or glands
  • few goblet cells
  • epithelium becomes simple columnar as diameter decreases - Clara cells
  • diameter determines airflow resistance
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10
Q

What is airflow resistance in the bronchioles controlled by?

A
  • smooth muscle
  • parasym - contraction
  • sym - relaxation
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11
Q

Terminal bronchioles

A
  • the end of the conducting portion, no alveoli
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12
Q

Respiratory portion

A
  • aka bronchial tree
  • alveoli are present
  • Clara cells secrete GAGs and proteins that protect the epithelium
  • smooth muscle
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13
Q

Respiratory bronchioles

A
  • beginning of respiratory portion, alveoli are present
  • first part of bronchial tree where gas exchange can occur - occurs in alveoli
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14
Q

Bronchial tree

A
  • respiratory bronchioles, alveolar ducts, alveolar sacs, alveoli
  • elastic and reticular fibers for distensibility and support
  • alveolar ducts - smooth muscle present, resemble knobs or drumsticks
  • alveolar sacs and alveoli
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15
Q

Alveolar sacs and alveoli

A
  • squamous epithelium
  • resemble pockets that air enters for gas exchange
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16
Q

Alveoli - Type 1 cells

A
  • epithelial cells
  • tight junctions
  • majority of the lungs surface area
  • most numerous cells in the gas exchange tissue
17
Q

Alveoli - Type 2 cells

A
  • rounded, usually found where alveoli unite
  • pulmonary surfactant - phospholipids, coat alveolar surfaces and reduce surface tension
18
Q

What are alveolar macrophages also called?

A

dust cells

19
Q

Intralveolar septum

A
  • capillaries and CT btwn adjacent alveolar epithelial cells
  • site of blood air barrier
  • Type 1 cell cytoplasm and membrane
  • capillary endothelial cell cytoplasm and membrane
  • fused basal lamina
  • elastic and reticular fibers
20
Q

Immotile ciliary

A
  • caused by defect in the protein dynein in cilia and flagella
  • causes chronic respiratory tract infections and male infertility
  • AKA kartagener’s syndrome
21
Q

COPD

A
  • chronic obstructive pulmonary disease
  • asthma, chronic bronchitis, emphysema
22
Q

Lung cancer

A
  • smoking is top risk factor and exposure to radon and asbestos
  • small cell lung carcinoma
  • metastasis to adrenal glands, bone, liver and brain
23
Q

What are the two types of lung cancer? How are they treated?

A
  • Small cell lung carcinoma - treated with radiation and chemo
  • non-small cell lung carcinoma - treated primarily with surgery and chemo depending on stage