Chapter 18 - Adrenergic Drugs Flashcards Preview

Nu 578: Ch 4-19 Exam 1 > Chapter 18 - Adrenergic Drugs > Flashcards

Flashcards in Chapter 18 - Adrenergic Drugs Deck (21):
1

the adrenergic antagonists can be neatly divided into two major groups

1. alpha-adrenergic blocking agents
2. beta-adrenergic blocking agents

2

Alpha antagonists lower blood pressure by causing vasodilation by blocking ____ receptors on arterioles and veins

alpha 1

3

In response to venous ______, return of blood to the heart decreases, thereby decreasing cardiac output, which in turn _____ arterial pressure.

dilation ; reduces

4

Overdose with an alpha-adrenergic agonist (eg, epinephrine) can produce _____

hypertension. It is caused by excessive activation of alpha 1 receptors on blood vessles

5

How do you reverse high blood pressure from overdose of an alpha-adrenergic agonist?

use an alpha-blocking agent

6

If an IV line containing an alpha agonist becomes extravasated, necrosis can occur secondary to _____

intense local vasoconstriction

7

What drug can be given to block vasoconstriction from infiltration?

phentolamine (aphpa-adrenergic antagonist)

8

______ results from proliferation of cells in the prostate gland

BPH

9

Symptoms of BPH can be controlled with drugs that block ______

alpha 1 receptors (causes reduced contraction of smooth muscles in the prostatic capsule and bladder neck.

10

Pheochromocytoma?

catecholamine-secreting tumor derived from cells of the sympathetic nervous system. (usually in adrenal medulla)

11

The principal cause of hypertension is activation of _____ receptors on blood vessels, although activation of beta1 receptors on the heart can also contribute

alpha 1

12

________ disease is a peripheral vascular disorder characterized by vasospasm in the toes and fingers.

Raynaud's

13

_____ blockers can supress symptoms by preventing alpha-mediated vasoconstriction

alpha

14

The most significant adverse effects of the alpha-adrenergic antagonists result from blockade of

alpha 1 receptors

15

______ is the most serious adverse response to alpha-adrenergic blockade

orthostatic hypotension

16

The cause of orthostatic hypotension is blockade of alpha receptors on ____

veins

17

Alpha-adrenergic antagonists can increase heart rate by triggering the

baroreceptor reflex

18

activation of ______ receptors is required for ejaculation

alpha 1

19

(nonselective) beta blockers (eg, propranolol), which block beta1 and beta2 receptors are ______ generation

first

20

(cardioselective) beta blockers (eg, metoprolol), which produce selective blockade of beta1 receptors (at usual doses) are _______ generation

second

21

(vasodilating) beta blockers (eg, carvedilol), which act on blood vessels to cause dilation, but may produce nonselective or cardioselective beta blockade are _______ generation

Third.