Chapter 19 Flashcards

(38 cards)

1
Q

virus

A

an infectious particle consisting of genes packaged in a protein coat

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2
Q

Can viruses reproduce or carry out metabolism outside of a host cell?

A

No

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3
Q

What 2 macromolcules make up viruses?

A

nucleic acid and protein (sometimes membrane envelope)

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4
Q

tobacco mosaic virus

A

first studied virus (crystallized)

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5
Q

Types of viral genomes

A

DNA or RNA

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6
Q

What shape is the genome of a virus?

A

linear or circular

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7
Q

What is the fewest number of genes a virus can have?

A

3

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8
Q

capsid

A

protein shell that encloses the viral genome

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9
Q

capsomeres

A

protein subunits that make up capsids

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10
Q

bacteriophages

A

viruses that infect bacteria (most complex capsids)

capsid head and protein tail (injects DNA inside)

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11
Q

viral envelopes

A

surround the capsids of influenza viruses and many other viruses in animals (derived from membranes of host cells)

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12
Q

obligate intracellular parasites

A

can replicate only within a host cell

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13
Q

host range

A

a limited number of host cells that it can infect

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14
Q

What happens when a viral genome enters a cell?

A

The cell begins to manufacture viral proteins

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15
Q

How do viral nucleic acid and capsomeres become new viruses?

A

spontaneous self-assembly

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16
Q

2 reproductive mechanisms of phages

A

the lytic cycle

the lysogenic cycle

17
Q

lytic cycle

A

phage replicative cycle that culminates in the death of the host cell through the lyses of the cell wall

18
Q

virulent phage

A

only uses lytic cycle to reproduce

19
Q

restriction enzymes

A

part of bacteria, attack phage DNA

20
Q

lysogenic cycle

A

replicates phages without destroying host

incorporates viral DNA into cell’s chromosome and then it is copied when the cell divides

21
Q

prophage

A

integrated viral DNA

22
Q

Can a virus switch from lysogenic to lytic? How?

A

Yes; environmental changes

23
Q

temperate phages

A

used lysogenic and lytic cycles

24
Q

2 variables used to classify viruses that infect animals

A

an RNA or DNA genome

a single-stranded or double-stranded genome

(many have additional envelope)

25
What binds to specific receptor molecules on the surface of a host cell?
viral glycoproteins on the envelope of the virus
26
What is used to form the viral envelope?
The host cell's plasma membrane or the host's nuclear envelope and then Golgi apparatus
27
retroviruses
use reverse transcriptase to copy their RNA genome into DNA
28
HIV (human immunodeficiency virus)
the retrovirus that causes AIDS (acquired immunodeficiency syndrome)
29
provirus
the viral DNA that is integrated into the host genome makes proviral DNA into RNA for mRNA and as genomes released from the cell
30
How long is a provirus part of the host?
Always
31
How may viruses damage or kill cells?
by causing the release of hydrolytic enzymes from lysosomes cause infected cell to produce toxins toxic envelope protein
32
Vaccines
harmless derivatives of pathogenic microbes that stimulate the immune system to mount defenses against the harmful pathogen
33
emerging viruses
those that suddenly become apparent
34
pandemics
global epidemics
35
What is true of most plant viruses?
RNA genome helical or icosahedral capsid
36
Mode of plant virus spread
horizontal transmission (enter through damaged cell walls) vertical transmission (inheriting the virus from a parent)
37
viroids
small circular RNA molecules that infect plants and disrupt their growth
38
prions
slow-acting, virtually indestructible infectious proteins that cause brain diseases in mammals (convert normal proteins into prion version)