Chapter 2.3 Flashcards

(37 cards)

1
Q

What causes sex-linked disorders? Are they recessive or dominant?

A
  • mutations in the gene of the X-chromosome
  • most of them are recessively inherited
  • > therefore, women inherit less of these sex-linked disorders
  • > because they have two sex chromosomes
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2
Q

Why are males termed hemizygous with respect to the X chromosome

A

-because they have only one copy of each gene on the X chromosome

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3
Q

What is a notable gene on the Y chromosome that initiates testis differentiation

A

-the SRY gene

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4
Q

What are the two functional parts of the testis

A

1) seminiferous tubules

2) interstitial cells(of Leydig)

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5
Q

Where are sperm produced in? What are they nourished by?

A
  • sperm are produced in the seminiferous tubules

- >they are nourished by the Sertoli cells

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6
Q

What hormone do cells of the Leydig secrete?

A
  • cells of the Leydig produce testosterone

- >they also produce other androgens

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7
Q

Where is the location of the testies? What is the temperature like there in comparison to the rest of the body?

A
  • the testies is located in the scrotum

- >the temperature there is 2 degrees to 4 degrees lower than the body

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8
Q

Where do sperm gain motility? Where do they go for ejaculation?

A
  • sperm gain motility in the vas deferens

- they go to the ejaculatory duct during ejaculation

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9
Q

Where do the two ejaculatory ducts?

A
  • in the urethra

- >it carries the sperm through the penis as they exit the body

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10
Q

What is the role of the seminal vesicles

A
  • contribute fructose to nourish the sperm
  • give sperm fluid mildly alkaline properties
  • > so it can survive in the vagina
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11
Q

What is the role of the prostate gland

A

-give sperm fluid mildly alkaline properties

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12
Q

What is the role of the bulbourethral gland

A
  • produces clear viscous fluid
  • > cleans out any remnants of urine
  • > lubricates the urethra during sexual arousal
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13
Q

What is semen

A

-a combination of sperm and seminal fluid

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14
Q

Describe the process of spermatogenesis

A

-it is the formation of haploid sperm through meiosis

  • in males diploid sperm are known as spermatogonia
  • after replicating their genetic material in the S stage
  • > they develop into primary spermatocytes
  • first meiotic division results in secondary spermatocytes
  • second meiotic division results in haploids called spermatids
  • finally spermatids mature to become spermatozoa
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15
Q

What do mature sperm consist of

A

-they consist of a head, midpiece and a flagellum

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16
Q

What is the midpiece filled with

A
  • it is filled with mitochondria

- >generates energy as the sperm swims through the female reproductive tract

17
Q

What is each sperm head covered by

A
  • an acrosome

- >is necessary to penetrate the ovum

18
Q

What is a major difference between the positioning of the female reproductive organs and the male reproductive organs?

A
  • unlike male reproductive system

- >all female reproductive organs are internal

19
Q

What hormones do the ovaries produce

A

-the ovaries produce estrogen and progesterone

20
Q

Describe where the egg goes after ovulation

A
  • it is released into the peritoneal sac
  • > in the abdominal cavity
  • it is then drawn into the fallopian tube
  • > which is lined with cilia to propel the egg forward
21
Q

What is the external female anatomy known as

A

-it is known as the vulva

22
Q

What kind of oocytes are the oogonia considered to be by birth? What do they develop into after menarche(menstrual cycle)

A
  • by birth
  • > all of the oogonia are considered to be primary oocytes
  • > these cells are 2n
  • > arrested in prophase 1
  • develop into secondary oocytes after menarche
  • > this is when one primary oocyte completes meiosis 1
  • > produces secondary oocyte
  • > secondary oocyte remains arrested in metaphase 2
23
Q

When does the secondary oocyte complete metaphase 2 and finish the remainder of meiosis 2

A
  • the secondary oocyte completes metaphase 2 once fertilization occurs
  • > then meiosis 2 is finished
24
Q

What two layers are the oocyte surrounded by

A
  • surrounded by:
  • > zone pellucida
  • > corona radiata
25
What is the purpose of the zone pellucida
- surround the oocyte itself - >an acellular mixture of glycoproteins - >protects the oocyte - >contains compounds necessary for sperm cell binding
26
What is the purpose of the corona radiata
- lies outside of the zona pellucida | - >layer of cells adhered to the oocyte during ovulation
27
Is GnRH allowed to be produced prior to puberty?
- no - >it is only released at the start of puberty -which then triggers the anterior pituitary to release FSH and LH
28
What is the role of LH and FSH in males
- FSH is to stimulate Sertoli cells - >triggers sperm maturation -LH cells causes interstitial cells to produce testosterone ->maintains male reproductive system ->responsible for secondary sexual characteristics eg; facial/axillary hair, deepening of the voice and changes in growth patterns
29
How does testosterone interact with the hypothalamus and the anterior pituitary
-it has a negative feedback on both of these structures
30
What is estrogen secreted in response to
-it is secreted in response to FSH ->results in the development of the female reproductive system and female secondary sexual characteristics eg; breast growth, change in fat distribution and widening of the hips
31
What is progesterone
- secreted by the corpeus luteum - involved in the development and maintenance of the endometrium - >not involved in the initial thickening of the endometrium - >that is the job of estrogen
32
Describe the characteristics of the follicular phase. When does it start? What hormones are in high amounts during this phase?
- begins when the menstrual flow starts - higher concentrations of GnRH=higher concentrations of FSH and LH - the ovarian follicles develop - follicles begin to produce estrogen - >estrogen has a negative feedback on the GnRH, LH and FSH
33
What are estrogen levels like during ovulation
- they reach a threshold - >results in positive feedback of GnRH, LH and FSH - >surge in LH is crucial, as this releases the ovum from the ovary
34
What hormone has high levels in the luteal phase? How does it affect GnRH, FSH and LH
- progesterone | - > it has negative feedback on the three hormones mentioned in the question
35
What is hCG or human chorionic gonadotropin?
- hormone is an analog of LH - >maintain the corpus luteum - it is crucial during the first trimester of development - >as the corpus luteum secrete estrogen/progesterone - >this keeps the uterine lining in place
36
Why do estrogen and progesterone need to be maintained at a high level during pregnancy
-so that there is negative feedback on GnRH secretion
37
What happens to FSH/LH levels during menopause? Also talk about estrogen and progesterone levels
- since there is no negative feedback on these two - >blood levels rise - estrogen and progesterone levels drop - >so endometrium lining is not maintained