Flashcards in Chapter 38 - Rosacea and Related Disorders Deck (16):
Which laser is used to recontour fibrotic rhinophyma?
CO2 laser; it's the only established method of improving fibrotic rhinophyma
Are the effects of isotretinoin on rosacea long lasting the way they are in acne patients?
No; most patients require longterm oral tetracyclines to maintain remission after treatment with isotretinoin
Pediatric patients with childhood granulomatous periorificial dermatitis can't be treated with tetracycline due to the risk of teeth staining. What oral antibiotic should be used instead?
Is topical tretnoin (a comedolytic) helpful in treating rosacea?
Yes, even though there are no comedones in rosacea. It may work through its effects on the elastolysis seen in chronic rosacea
Is azelaic acid cream as effective as topical metronidazole for treating rosacea?
Yes, it appears to be as effective as topical metronidazole
What's the name for the eponymously named syndrome, presumed to be AD, where patients develop early-onset rosacea-like facial dermatosis, plus comedones, pitted atrophy, and small papules?
*In some patients there's an overlap with Dowling-Degos disease
What's the name of the rosacea that often clinically overlaps with granulomatous rosacea, has a predilection for the periorbital region, and is characterized histologically by granulomas with central caseation necrosis?
Lupus miliaris disseminatus faciei
*Despite the granulomas with central caseation, there's no relationship to Mycobacterium tuberculosis
What is the other name for ulerythema ophryogenes?
Keratosis pilaris atrophicans faciei
*Follicular atrophy and scarring alopecia of the eyebrows is typical
What is the pathogenesis of rosacea?
Multifactorial. Vasodilation, hyperirrtability, organisms (Demodex folliculorum, Propionibacterium acnes), neurologic diseases, drugs, ?UV light, ?photodamage, vasoactive tumors/disorders
What are the 4 subtypes of rosacea?
1) erythematotelangiectatic, 2) papulopustular, 3) phymatous, 4) ocular
What are the primary features of rosacea?
Flushing, non transient erythema, papules/pustules/ telangiectasia
What is the diagnostic criteria for rosacea?
1 or more primary features
What is the pathogenesis for ocular rosacea?
Meibomian gland impaction leads to decreased lipid in the tear film, greater tear evaporation, and subsequent irritability of the eye. ?Elevated epithelium-derived protease activity
What are some ocular symptoms of rosacea?
Symptoms range from a sensation of dryness or tired eyes to edema, tearing, pain, blurry vision, styes, chalazia and corneal damage
What might you see on physical examination of the eyes in a patient with ocular rosacea?
Blepharitis, conjunctivitis, chronic edema, meibomian impaction, styes, keratitis, corneal neovascularization, corneal ulceration, rupture, ectropion