Chapter 4: CNS Flashcards
Glial cells of the PNS
- satellite cells
- Schwann cells
Satellite cess
Form capsule around the cell body
Schwann cells
- form myelin
- provides neurotrophic factors (growth)
Glial cells of the CNS
- oligodendrocytes
- astrocytes
- microglia
- epidymal cells
Oligodendrocytes
Forms myelin
Astrocytes
- secretes paracrine signals
- forms tight junctions (BBB)
- provide neurotrophic nature
Microglia
- brains immune cells
- scavengers
What happens if microglia are overactive
Damage to the brain cells
- alztimers, dementia, AIDS, MS
Ependymal cells
- secrete cerebral spinal fluid
- act as stem cells
What is the infection of the meninges
Menigitis
Dura mater
- tough outer membrane
- houses veins
Pia mater
- innermost layer
- houses arteries
How many times a day is cerebrospinal fluid
3 times
125-150ml each time it is made
What does cerebrospinal fluid do chemically
- increases sodium allows communication
What does cerebrospinal fluid do at the physical value
- shock absorber
- reduces to weight of the brain tissue by increasing buoyancy
What is the blood brain barrier produced by
- astrocytes
BBB
- tight junction secreted
- selectively transported
What is a diseas of the BBB
- Parkinson’s disease
Parkinson’s disease
BBB
- loses dopeninergic neurons
Treatment: leva-dopa
Where is there an absence of BBB
- vomiting center
- hypothalamus
What is the werneckis area responsible for
Language comprehension
What is the Broca’s area responsible for
Formation of speech
Receptive aphasia
Cannot attach meaning to words
Expressive aphasia
- no sentence formation
- no syntax