Chapter 5 Flashcards
(35 cards)
Membranes are composed of _____ and _____
phospholipids and proteins
Many phospholipids are made from _______ fatty acids that have kinks in their tails
unsaturated
Unsaturated fatty acids in phospholipid bilayer
Prevent them from packing tightly together, which keeps them liquid.
Integrins
Give the membrane a stronger framework.
Integrins attach to the extracellular matrix on the outside of the cell as well as span the membrane to attach to the cytoskeleton.
Glycoproteins in the membrane
Serve as identification tags that are specifically recognized by membrane proteins of other cells.
Carbohydrates in the extracellular matrix
Significantly involved in cell-cell recognition
Peripheral proteins
Proteins bound to the surface of the membrane
Integral proteins
Proteins that penetrate the hydrophobic core
Transmembrane proteins
Integral proteins that span the membrane
Six major functions of membrane proteins
- Transport
- Enzymatic activity
- Signal transduction
- Cell-cell recognition
- Intercellular joining
- Attachment to the cytoskeleton and extracellular matrix (ECM)
Membrane carbohydrates in cell-cell recognition
Cells recognize each other by binding to molecules, often containing carbohydrates, on the extracellular surface of the plasma membrane.
Membrane carbohydrates may be covalently bonded to lipids (forming glycolipids) or more commonly to proteins (forming glycoproteins).
Carbohydrates on the external side of the plasma membrane vary among species, individuals, and even cell types in an individual.
The asymmetrical distribution of proteins, lipids, and associated carbohydrates in the plasma membrane are determined when ______________.
the membrane is built by the ER and Golgi apparatus
Glycolipid
A sugar covalently bound to a lipid
Glycoprotein
A sugar covalently bound to a protein
Because membranes allow some substances of cross or be transported more easily than others, they exhibit ______________
selective permeability
Nonpolar molecules (CO2 and oxygen) cross the cell membrane _____
easily
Polar molecules (glucose and other sugars) cross the membrane ______
without ease
Passive transport
Does not use energy to transport molecules across the membrane
Diffusion
A process in which particles spread out evenly in an available space
Particles move from an area of more concentrated particles to an area where they are less concentrated
Eventually, the particles reach equilibrium where the concentration of the particles is the same throughout
Concentration gradient
In diffusion, the difference in concentration of particles inside and outside the cell membrane
Osmosis
The diffusion of water across a selectively permeable membrane.
Water moves across membranes in response to solute concentration (lower to higher) until the solute concentration is equal on both sides.
Tonicity
The ability of a surrounding solution to cause a cell to gain or lose water.
Isotonic
Indicates the concentration of a solute is the same on both sides.
Hypertonic
Indicates that the concentration of a solute is higher outside the cell.