Chapter 5: Evaluation of Cell Morphology and Intro to platelet and WBC morphology

Question 1

a prominent morphological clue when suspecting lead poisoning is the presence of which of the following on a peripheral smear?

Answer 1

basophilic stippling

Question 2

In what disease would you expect to find oval microcytes on the peripheral smear?

Answer 2

megoblastic anemia

Question 3

what are some possible mechanisms for the production of macrocytes

Answer 3

postsplectomy status
pernicious anemia
liver disease

Question 4

an abnormal erythrocyte seen in liver disease and hemoglobinopathies and thalassemia and is characterized by the “bulls eye” area is known as

Answer 4

target cell

Question 5

morphological abnormaliteit found in cases of severe burns, microangiopathic hemolytic anemias, and disseminated intravascular coagulation or DIC are

Answer 5

schistocytes

Question 6

oat shaped cells may be associated with

Answer 6

sickle cell

Question 7

how would a cell be classified that has a diameter or 9 micrometers and MCV of 104 fL

Answer 7

macrocytic

Question 8

abnormal platelet morphology may be observed most predominantly in

Answer 8

idiopathic myelofibrosis

Question 9

what type of red cell inclusion is a DNA remnant?

Answer 9

Howell-jolly body

Question 10

what is a microcytic/hypochromic anemia

Answer 10

IDA

Question 11

a hyperhsegmented neutrophil may be seen in which anemia

Answer 11

megablastic

Question 12

precipitates of denatured hgb found primarily in patients with hemolytic anemia resulting from oxidant stress describes

Answer 12

heinz bodies

Question 13

pappenheimer inclusions are formed from

Answer 13

express iron

Question 14

RBC inclusion resulting from an acceleration in hgb biosynthesis and consists of RNA

Answer 14

basophilic stippling

Question 15

RBC with large area of central pallor

Answer 15

hypochromasia

Question 16

variation in the size of the RBC

Answer 16

anisocytosis

Question 17

also known as codacytes

Answer 17

target cells

Question 18

rbcs appearing stacked on each other

Answer 18

rouleaux

Question 19

MCV of 65%

Answer 19

microcytic

Question 20

RBCs with mouthlike pallor

Answer 20

stomatocytes

Question 21

rbcs w/o an area of central pallor

Answer 21

microspherocytes

Question 22

rbcs with evenly distributed spicules on the membrane

Answer 22

echinocytes or burr cells

Question 23

rbc fragments

Answer 23

schistocytes

Question 24

rbcs appearing bluish in color

Answer 24

polychromasia

Question 25

variation in the shape of RBC

Answer 25

poikilocytosis

Question 26

congenital abetalipoproteinemia

Answer 26

acanthocytes

Question 27

the formation of a vacuole in an RBC trapped by fibrin

Answer 27

blister cells

Question 28

formed when an RBC with an inclusion squeezes out of a tight space

Answer 28

dacrocytes or teardrop cells

Question 29

seen in HbS disease

Answer 29

depranocyte

Question 30

pappenheimer bodies stain

Answer 30

wright stain

Question 31

sideritic granules stain

Answer 31

prussian blue stain

Question 32

Hbc

Answer 32

hexagonal shaped crytsal inclusions

Question 33

HbSC disease

Answer 33

fingerlike projections

Question 34

Holly jolly, papperheimer, basophilic stippling may be seen in

Answer 34

Romanowsky type stain like Wright and supra vital stain like new methylene blue

Question 35

helmet cells associated with patients who have

Answer 35

G6PD syndrome and occur as a result of Heinz formation