Chapter 5 - Linkage/Mapping Flashcards

1
Q

violation of Mendel’s 2nd Law

A

genes linked on the same chromosome segregate together

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2
Q

the greater the distance between the genes,

A

the greater the chance of crossovers

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3
Q

crossovers occur at

A

prophase I of meiosis

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4
Q

independent assortment always gives

A

50% recombination

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5
Q

recombination frequency

A

recombinant strands per total strands progeny per meiosis

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6
Q

accurate map distances

A

less than 7 mu

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7
Q

why recombination frequency underestimates true map distance

A

double crossovers between two loci will restore at least some parental genotypes

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8
Q

coefficient of coincidence

A

the observed number of DCOs divided by the expected number of DCOS

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9
Q

interference equation

A

1 - CoC

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10
Q

interference definition

A

observed double crossover frequency differs from the expected double crossover frequency

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11
Q

positive interference

A

one crossover reduces the likelihood of a second simultaneous crossover

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