Chapter 5 review Flashcards

1
Q

What is the role of the plasma membrane?

A

separate intracellular fluid and extracellular fluid
regulate movement in and out of the cell

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2
Q

What factors affect membrane fluidity?

A

unsaturated fatty acids - love water
cholesterol - fewer fluids
inc temperature - inc fluidity

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3
Q

What two types of proteins are associated with membranes?

A

integral and peripheral proteins

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4
Q

What are the names of lipids and proteins when they have a carbohydrate attached to them?

A

Glycolipids & Glycoproteins

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5
Q

What are the components of a solution? How would you calculate the concentration of
a solution? What is osmolarity?

A

Solution: made up of solvents and solutes
Calculate: ___/mol
Osmolarity: concentration of all solute particles in solution

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6
Q

Does passive membrane transport require ATP? What are the three types of passive membrane transport?

A

No ATP
examples: simple diffusion, facilitated diffusion, osmosis

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7
Q

What is the definition of diffusion?

A

when molecules/ions go from an area of a high concentration to a low concentration

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8
Q

What are the characteristics of solutes that determine whether or not they can pass across a phospholipid bilayer? Would you expect an amino acid to pass across?

A

Lipid solubility - must be non-polar
size of molecule
yes an amino acid can cross due to small size

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9
Q

What are the two types of facilitated diffusion? What types of solutes, and what two types of proteins are involved? Is any input of energy needed?

A

Channel mediated diffusion and Carrier mediated diffusion
Carrier mediated: carrier alters shape for transport ex. sugars and amino acids
Channel mediated: substances diffuse through channels
leak channel open, gated channel: controlled by chemical or electrical signals ex. water, ions like salt

NO ENERGY IS NEEDED FOR EITHER

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10
Q

Describe simple diffusion

A

Diffusion of molecules directly though the bilayer
- nonpolar ex gasses, steroid hormones, fatty acids

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11
Q

What is the definition of osmosis? When does it occur? What direction does water move in? What is meant by osmotic pressure?

A

Diffusion of a solvent through a selectively permeable membrane
when: concentration of water differs on two sides of the membrane
Water moves from a more dilute to less dilute solution

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12
Q

Why is osmosis important for homeostasis?

A

distribution of water and fluid ex. healthy indv ECF=ICF

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13
Q

At equilibrium can both sides have the same osmolarity but different volumes?

A

yes

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14
Q

Isotonic solutions

A

Same concentration of non-penetrating solutes inside the cell

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15
Q

hypertonic solutions

A

higher concentration outside than inside of the cell makes cells shrink
ex. salt water

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16
Q

Hypotonic solutions

A

higher concentration inside the cell inside than outside
cells will swell
ex. pure water

17
Q

How does active transport differ from facilitated diffusion?

A

movement of substances against the concentration gradient or movement of large substances
- ATP required

18
Q

What does active transport require:

A

membrane protein and energy

19
Q

Two types of active transport?

A

primary active transport
secondary active transport

20
Q

Primary active transport?

A

substance binds to a transmembrane protein
hydrolysis of ATP
Phosphorylation of transmembrane protein
protein changes shape
substance goes to other side

21
Q

Describe the sodium-potassium pump

A

3 sodium 2 potassium in
Atp binds with 3 na
Na binding causes ATP hydrolysis and pump changes shape
Na is released
K+ (potassium binds) and phosphate is released
Potassium in

22
Q

Describe secondary active transport

A

coupling - one subtance goes against and one goes down
energy through substance going down

23
Q

Symport transport

A

one direction

24
Q

Antiport transport

A

both directions

25
What are the two types of vesicular transport?
ways to transport large particles Endocytosis: substances move inside call Exocytosis: substances moved outside cell
26
By what 3 mechanisms are materials endocytosed?
Phagocytosis: cells engulf the large particle at once Pinocytosis: cell gulps tiny fluid receptor-mediated endocytosis: receptor proteins tell which substances to enter
27
How are proteins exported from the cell, and what is this process called?
Exocytosis - transport to the ECF
28
What are the two types of local signaling and the one type of long distance signaling called?
Local signaling: paracrine: molecules released by cell acts on nearby cells synaptic: nerve cell releasing neurotransmitters to a synapse Long distance: endocrine: endocrine cells releasing hormones into body fluids
29
Ligands?
signaling molecules that bind to receptors
30
Receptor? what are the 2 types:
Proteins in plasma membrane - G protein coupled receptors (GPCRs) - ligand-gated ion channels
31
How do GCPRs work?
Ligand binds to GPCR Gpcr activated changes shape G protein binds to GPCR GTP binds to G protein G protein leaves GCPR and diffuses alng membrane G protein binds enzyme and changes enzyme shape cellular response occurs