chapter 5.2

Question 1

Recombination helps ensure

Answer 1

proper chromosome segregation during meiosis I

Question 2

Syntenic genes

Answer 2

genes located on the same chromosome

Question 3

genes close together are

Answer 3

We consider these pairs of genes “linked”.

Question 4

Two genes with high recombination frequency are

Answer 4

further apart

Question 5

Two genes with low recombination frequency

Answer 5

are closer together

Question 6

Recombination frequencies can be used to

Answer 6

estimate the relative distance between 2 genes

Question 7

How do you determine if 2 genes are linked?

Answer 7

the Chi Square test

Question 8

Null hypothesis rejection means

Answer 8

genes are linked

Question 9

Genes on different chromosomes will always

Answer 9

assort independently

Question 10

Why don’t the recombination frequencies add up exactly?

Answer 10

Because of double cross over events

Question 11

Formula for Rf

Answer 11

recombo/ total x 100
rf= mu=cM

Question 12

: What is the order of 3 genes, A B and C?

Answer 12

First, calculate the RF between each pair of genes, then assemble into an order with the pair with the largest RF on the outside.

Question 13

Genes that are closer together, will reflect a more accurate RF value, because

Answer 13

they minimize the chance of double cross over events

Question 14

when mapping

Answer 14

Start with the genes that are closest together, since these will be the most accurate distances