CHapter 6 Flashcards
(6 cards)
1
Q
relationship between substrate concentration and initial velocity
A
Vo = Vmax (M) / Km + M
2
Q
Trypsin, Chymotryposin and Elastase cleave at what amino acids
A
- lysine and arginine
- phenalaline and tyrisine
- glycine and alanine
3
Q
regulation of enzyme activity comes in two parts
A
covalent modification (phosphorylation) -non covalent (allosteric regulation)
4
Q
6 properties of allosteric enzymes
A
- regulated by intermediates
- modulators mind to them
- usually are quaternary structures
- catalyze branch point reactions
- are slow
- have sigmoidal curves
5
Q
when the ratio of PEP/ADP is high:
when the ratio of PEP/ADP is low:
A
- PFK is inhibited
- PFK is activated
6
Q
substrates and activators of allosteric enzymes may only what while inhibitors many only what
A
bind to the R state and may only bind to the T state
