chapter 6 - cell division Flashcards
what is interphase
cell preparing for cell division
what happens during interphase
dna is replicated and checked for errors
protein synthesis occurs in cytoplasm
mitochondrai grow and divide in cytoplasm
chloroplasts grow and divide in algal cell cytoplasm
normal metabolic processes occur
what happens during g1 of interphase
proteins which synthesise organelle are produced so organelles replicate. Cell increases in size
what happens during S of interphase
dna is replicated in nucleus
what happens during g2 of interphase
cell continues to increase in size, energy stores are increased and duplicated DNA is checked for errors
what is mitosis
when nucleus divides
what is cytokinesis
when cytoplasm divides and 2 cells are produced
what is g0
when cell leaves the cycle temporarily or permanently
why does g0 happen
-cell becomes specilaised no longer able to divide
-DNA of cell may be damagaed so can no longer divide. Cell becomes senescent
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what does a high number of senescent cells cause
age-related diseases such as cancer and arthritis
what type of cells can enter g0 can go back to cell cycle
lymphocytes in an immune response
what happens during g1 checkpoint
at the end of g1 phase. Checks for cell size, nutrients, growth factors and DNA damage
what happens during g2 checkpoint
checks for cell size, DNA replication, DNA damage
what happens during spindle assembly checkpoint
checks if chromosomes attach to spindles
what do kinases do
they are enzymes catalysing addition of phosphate group which changes tertiary structure of checkpoint protein activating them during cell cycle
what are checkpoint proteins called
cyclins
what is CDK complex
cyclin- dependent kinase complex
how are tumours formed
cyclin gene may be mutated causing large amount of cyclins to be formed therefore disrupting regulation of cell cycle causing tumour. CDK can be used as chemical inhibitor to treat cancer
is mitosis sexual or asexual
asexual - produce genetically identical offspring
what is mitosis used for
growth , replacement , and repair of tissues, asexual reproduction
what is binary fission
bacteria version of mitosis as they do not have a nucleus
how are chromatids formed
during interphase, each DNA molecule ( chromosomes) is converted to 2 identical DNA molecules, called chromatid
what is the region where 2 chromatids are joined together
centromere
how many chromosomes are there when 2 chromatids are formed from one chromosome
still 1