Chapter 6: Contraction of Skeletal Muscle Flashcards

(67 cards)

1
Q

how many percent of the body is skeletal muscle

A

40%

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2
Q

how many percent is smooth
and cardiac muscle in the body?

A

10%

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3
Q

The sarcolemma consists of a true cell membrane, called
the?

A

plasma membrane

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4
Q

outer coat made
up of a thin layer of polysaccharidematerial that
contains numerous thin collagen fibrils

A

plasma membrane

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5
Q

turn collect into bundles to form the muscle tendons thatthen insert into the bones.

A

tendon fibers

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6
Q

Each muscle fiber contains
several hundredto several thousand

A

myofibrils

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7
Q

Each myofibril is composed
of about?

A

1500 myosin filaments and 3000 actin filaments

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8
Q

The light
bands contain only actin filaments and are called?

A

I bands

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9
Q

dark bands contain

A

myosin filaments

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10
Q

ends of the actin filaments where they
overlap the myosin, and are called?

A

A bands

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11
Q

the small projections from the sides of the
myosin filaments

A

cross-bridges

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12
Q

ends of the
actin filaments are attached to a so-called?

A

Z-discs

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13
Q

composed of
filamentous proteins different from the actin and
myosin filaments

A

Z disc

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14
Q

The portion of the myofibril (or of the whole
muscle fiber) that lies between two successive Z
discs is called a?

A

sarcomere

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15
Q

at
this length the muscle is capable of generating its greatest force of contraction called

A

sarcoplasm

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16
Q

sarcoplasm surrounding the myofibrils
of each muscle fiber is an extensive reticulum called the ?

A

sarcoplasmic reticulum

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17
Q

This
reticulum has a special organization that is extremely important in controlling muscle contraction

A

sarcoplasmic reticulum

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18
Q

achieved by a large number of filamentous molecules
of a protein called?

A

titin

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19
Q

acts on a local area of the
musclefiber membrane to open multiple
“acetylcholine-gated
”cation channels through
protein molecules floating inthe membrane

A

acetylcholine

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20
Q

initiate attractive forces
between the actin and myosin filaments, causing them to slide along side each other, which is
the contractile process

A

calcium ions

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21
Q

the Z discs have been
pulled bythe actin filaments up to the ends of
the myosin filaments. Thus, muscle contraction
occurs by a

A

sliding filament mechanism

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22
Q

what causes the actin filaments to slide
inward among the myosin filaments?

A

caused by forces generated by interaction of the
cross-bridges from the myosin filaments with the
actin filaments.

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23
Q

The backbone of
the actin filament is a double-stranded

A

F-actin protein molecule

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24
Q

Each strand of the double F-actin helix is
composed of polymerized

A

G actin molecules

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25
the active sites on the actinfilaments with which the cross-bridges of the myosin filaments interact to cause muscle contraction
ADP molecules
26
Attached to one end of each tropomyosin molecule is a
troponin
27
The actin filament also contains another protein
tropomyosin
28
Attached intermittently along the sides of the tropomyosin molecules are still other protein molecules called
troponin
29
has a strong affinity for actin
troponin I
30
subunits for tropomyosin
troponin T
31
subunits for tropomyosin
troponin T
32
subunits for calcium ions
troponin C
33
The new alignment of forces causes the head to tilt toward thearm and to drag the actin filament along with it
power stroke
34
the greater the amount of work performed by the muscle, the greater the amount of ATP that is cleaved
fenn effect
35
the increase in tension that occurs during contraction
active tension
36
contracts rapidly when it contracts against no load—to a state of full contraction in about 0.1 second for the average muscle
skeletal muscle
37
When a muscle contracts against a load, it performs
work
38
The second important source of energy, which is used to reconstitute both ATP and phosphocreatine
glycolysis
39
third and final source of energy. means combining oxygen with theend products of glycolysis and with various other cellular foodstuffs to liberate ATP
oxidative metabolism
40
3 sources of energy for muscle contractions
1. phosphocreatine 2. glycolysis 3. oxidative metabolism
41
what do you call of muscle contraction when the muscle does not shorten during contraction
isometric
42
when it does shorten but thetension on the muscle remains constant throughout the contraction
isotonic
43
Muscles that react rapidly, including anterior tibialis
fast muscle fibers
44
muscles such as soleus that respond slowly but with prolonged contraction
slow fibers
45
Slow Fibers (Type 1, Red Muscle)
(1) Smaller fibers (2)Also innervated by smaller nerve fibers (3) More extensive blood vessel system and capillaries to supply extra amount of oxygen (4) Greatly increased numbers of mitochondria,also to support high levels of oxidative metabolism (5) Fiber Contain large amounts of myoglobin, an iron-containing protein similar to hemoglobin in red blood cells
46
The myoglobin gives the slow muscle a reddish appearance andthe name?
red muscle
47
Fast Fibers (Type II, White Muscle)
(1) Large fibers for great strength of contraction (2) Extensive sarcoplasmic reticulum for rapid release of calcium ions to initiate contraction (3) Large amounts of glycolytic enzymes for rapid release of energy by the glycolytic process (4) Less extensive blood supply because oxidative metabolism is of secondary importance (5) Fewer mitochondria, also because oxidative metabolism is secondary
48
A deficit of red myoglobin in fast muscle gives it the name
white muscle
49
All the muscle fibers innervated bya single nerve fiber are called a
motor unit
50
means the adding together of individual twitch contractions to increase the intensity ofoverall muscle contraction
summation
51
Summation occurs in two ways;
✓ multiple fiber summation ✓ frequency summation
52
increasing the number of motor units contracting simultaneously
multiple fiber summation
53
increasing the frequency of contraction
frequency summation
54
frequency summation can lead to?
tetanization
55
When the frequency reaches acritical level, the successive contractions eventually become so rapid that they fuse together and the whole muscle contraction appears to be completely smooth and continuous
tetanization
56
the strength of contractionincreases to a plateau, a phenomenon called the?
staircase effect or treppe
57
Even when muscles are at rest, a certain amount of tautness usually remains. This is called?
muscle tone
58
study of different types of muscles, lever systems, and their movements is called?
kinesiology
59
total mass of a muscle increases
muscle hypertrophy
60
total mass of a muscle decrease
muscle atrophy
61
causing enlargement of the individual muscle fibers
simple fiber hypertrophy
62
occurs to a much greater extent when themuscle is loaded during the contractile process
hypertrophy
63
The pathway that appears to account for much of the protein degradation in a muscle undergoing atrophy is the
ATP dependent ubiquitin- proteasome pathway
64
increase in fiber number
fiber hyperplasia
65
fibrous tissue that replaces the muscle fibers during denervation atrophy also has a tendency to continueshortening for many months, which is called
contracture
66
causes large motor units
macromotor units
67
muscles of the body go into a state of contracture called? that is, the muscles contract and become rigid
rigor mortis