Chapter 6:DNA structure and replication Flashcards

1
Q

What does DNA stand for?

A

Deoxyribonucleic Acid

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2
Q

What is a gene?

A

Genetic material is carried and stored in coded in genes, one section of DNA and can be switched off on and by other genes

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3
Q

What does expressed mean?

A

A gene switched on

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4
Q

Where is DNA found in Eukaryotes?

A

Nucleus, chloroplasts and mitochondria

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5
Q

What is chromatin?

A

DNA in a non-dividing cell which only appears grainy and undefined under a microscope

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6
Q

What happens to chromatin when a cell prepares to divide?

A

Condenses by coiling up and thickens allowing individual chromosomes to be seen

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7
Q

What is a chromosome?

A

One molecule of DNA with its associated proteins

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8
Q

How is DNA displayed?

A

Double stranded molecule

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9
Q

What is an unduplicated chromosome?

A

A long double helix molecule coiled around a histone protein

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10
Q

What is a histone?

A

A protein that DNA winds around in eukaryotic cells

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11
Q

What are sister chromatids?

A

Two identical copies of a single chromosomes, formed by replication and connected by centromere

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12
Q

What is a centromere?

A

A waist like construction in a chromosome required for the movement of chromosomes during cell division

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13
Q

What shape do sister chromatids and centromeres form?

A

X shape

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14
Q

When are chromosomes visible?

A

Prior to division stage and after replication has occurred

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15
Q

What are homologous chromosomes?

A

pair of chromosomes that have the same size, shape and genes at the same location

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16
Q

Where do the chromosomes come from in homologous chromosomes pairs?

A

One is inherited from each parent

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17
Q

What is karyotype?

A

The display of the number and appearance of the chromosomes of organisms or observed in metaphase

18
Q

How many pairs of chromosomes do humans have?

A

23 pairs (46 chromosomes)

19
Q

What is the endosymbiotic theory?

A

A theory that suggests chloroplast and mitochondria arose from ancient prokaryote cells that were ingested by other prokaryote host cells

20
Q

What is maternal inheritance?

A

Inheritance only from mothers; any trait that is encoded by organelle DNA only from mother

21
Q

What is a nucleoid?

A

The region within a prokaryotic cell that contains the genetic material.

22
Q

Where are chromosomes join in prokaryotic cells?

A

A single circular chromosome which lies within the cytoplasm. Chromosomes often join to plasma membrane.

23
Q

What is plasmid?

A

A small circular piece of DNA found in bacteria which can replicate independently of the cell’s chromosomes

24
Q

What is a nucleotide?

A

The basic building block of nucleic acids linked by phosphodiester bonds

25
What are nucleotides made of?
five-carbon sugar, a phosphate group and nitrogenous base.
26
What are the 4 kinds of nitrogenous bases in DNA?
Adenine, thymine, guanine and cytosine
27
What is complementary bases?
The nitrogenous bases on nucleotide that bind to each other
28
What are complementary bases that bind?
A to T and C to G
29
What holds the double helix together?
Hydrogen bonds
30
What does antiparrell mean and do double helix have it?
Yes, it means they run the opposite ways
31
How is RNA different to DNA?
RNA is a single strand chain of nucleotides, thymine is replaced by base uracil and ribs sugar replaces deoxyribose of DNA
32
How is RNA useful?
It is useful in protein synthesis
33
Why does DNA replicate?
Growth, repairs and reproduction
34
What is a daughter cell?
Either of the two cells formed during cell division
35
What is the start of cell division?
The enzyme helicase which helps the double helix unwind by breaking the hydrogen bonds and separate
36
How does Helicase unwind and separate the strands?
By breaking the hydrogen bonds exposing the nucleotide bases
37
What is parental DNA?
The DNA of the original cell
38
What happens during interphase?
Active growth, synthesis of DNA and preparation of next division
39
What is a replication fork?
The junction between unwound DNA and joined DNA
40
What is DNA polymerase?
An enzyme capable of making exact copies of DNA fragments
41
What happens after hydrogen bonds are broken?
DNA polymerase attaches the appropriate base pair to expose nucleotide running in a 3 prime to 5 prime
42
What is semiconservative replication?
A double helix consisting of a parental strand and daughter stand. Is the outcome during cell division